Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID05225428

Video Education With Result Dependent Disclosure to Improve Genetic Testing Access for Hereditary Cancer Risk

Led by Dana-Farber Cancer Institute · Updated on 2026-05-22

1020

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

Sponsors

D

Dana-Farber Cancer Institute

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating strategies to improve the accessibility of the Video Education with Result Dependent Disclosure (VERDI) model, which is used as a pre-genetic testing education alternative for people at risk of hereditary cancers including breast, ovarian, pancreatic, prostate, colorectal, renal cancers, melanoma, and sarcoma. The study aims to better serve a diverse patient population by refining and testing this educational approach compared to standard genetic counseling. The study has two parts. The first part involves a qualitative assessment where about 20 participants watch an 8-minute educational video about genetic testing for inherited cancer risk and then complete a short interview by video or phone. The second part is a randomized controlled trial with 1000 participants comparing the VERDI video education model to standard genetic counseling. Both interventions are behavioral in nature, focusing on education about genetic testing. Participants will be involved by watching the educational video and/or receiving genetic counseling, followed by interviews or assessments. Researchers will measure outcomes such as the acceptability of the video education through qualitative interviews conducted within three weeks. The study includes informed consent, and participants must be able to understand English or Spanish. The total duration and follow-up details vary by study part.

CONDITIONS

Brief Title

Video Education With Result Dependent dIsclosure

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Current or prior diagnosis of breast cancer, ovarian cancer, pancreatic cancer, prostate cancer, colorectal cancer, renal cancer, melanoma, or sarcoma
  • Ability to understand spoken or written English or Spanish in a healthcare context
  • Ability and willingness to sign a written informed consent document
  • Black or Latinx individuals (for qualitative assessment study only)
Not Eligible

You will not qualify if you...

  • Prior cancer genetic testing
  • Prior germline genetic testing
  • Active hematologic malignancy such as chronic lymphocytic leukemia
  • Currently pregnant
  • Currently incarcerated

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote)

Outpatient Treatment

Duration - Single session

Participants watch an 8-minute educational video about genetic testing for inherited cancer risk followed by either standard genetic counseling or the VERDI model intervention.

1 visit (in-person or remote)

Trial Site Locations

Total: 1 location

1

Dana Farber Cancer Institute

Boston, Massachusetts, United States, 02115

Actively Recruiting

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Research Team

H

Huma Q. Rana, MD. MPH

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

3

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