Actively Recruiting

Phase 2
Age: 18Years - 80Years
All Genders
ID04611009

Treatment Effect and Relevance on Daily Life of a Video-supervised Sensorimotor Training Program and Its Influence on the Pathophysiology in Writer's Cramp

Led by University Hospital Schleswig-Holstein · Updated on 2024-12-10

54

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Writer's cramp is a common task-specific movement disorder that causes involuntary muscle contractions during writing, often impacting daily life and work. This research evaluates the effectiveness of two different year-long training programs for people with writer's cramp. The study compares a sensorimotor training program with an awareness training program, aiming to develop a practical therapy accessible to patients regardless of location. The study is conducted by the University Hospital Schleswig-Holstein and includes brain imaging to explore changes in brain function. Participants will be randomly assigned to one of two groups: one receiving sensorimotor training focused on improving finger and wrist movements, progressing to specific writing exercises after four weeks; the other group will engage in mindfulness exercises designed to increase present-moment awareness of self and surroundings. Both groups will be supervised via video calls to support their practice. The interventions last twelve months, with ongoing monitoring. Throughout the study, participants will undergo regular assessments at months 4, 8, and 12, including the Canadian Occupational Performance Measure to capture patient-centered outcomes, clinical scales for symptom evaluation, and detailed computer-based writing analysis. Functional MRI scans will be conducted to assess brain network changes during writing tasks. Additional interviews and reaction time tasks will provide further insights. The study promises minimal risk, with MRI procedures comparable to standard non-contrast scans.

CONDITIONS

Brief Title

Video-supervised Motor and Awareness Training in Writer's Cramp

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Right handed idiopathic writer's cramp according to standardized criteria, including various dystonic postures
  • Ability to participate in video calls
  • Age between 18 and 80 years
Not Eligible

You will not qualify if you...

  • Presence of additional neurological or psychiatric diseases
  • Left-handed individuals
  • Botulinum toxin treatment within the last 3 months or remaining weakness from previous injection
  • Use of anticholinergic or sedating medications
  • Cardiac pacemaker, electronic or metal implants
  • Pregnancy or suspected pregnancy
  • Severe ametropia or anxiety in small rooms preventing MRI
  • Inability to participate in video calls

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote)

Outpatient Treatment

Duration - 12 weeks

Participants undertake either motor training involving finger and wrist movements with additional writing exercises after four weeks, or mindfulness awareness training through video-supervised sessions.

Weekly video-supervised sessions

Follow-up

Duration - Up to 12 months

Participants are assessed to evaluate changes from baseline up to 12 months after treatment, including occupational performance and writing function.

Visits at month 4, 8, and 12 for assessments

Trial Site Locations

Total: 1 location

1

Kiel University

Kiel, Schleswig-Holstein, Germany, 24105

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Research Team

K

Kirsten E Zeuner, Prof. MD

A

Arne Knutzen, M.Sc. OT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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