Actively Recruiting

Phase 2
Age: 18Years - 80Years
All Genders
NCT04611009

Video-supervised Motor and Awareness Training in Writer's Cramp

Led by University Hospital Schleswig-Holstein · Updated on 2024-12-10

54

Participants Needed

1

Research Sites

340 weeks

Total Duration

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AI-Summary

What this Trial Is About

Writer's cramp is the most common task-specific dystonia. It is characterized by involuntary co-contraction of antagonistic muscles during writing. This disabling condition may force patients to give up their occupation. In this study the efficacy of a twelve months long-term training in patients with writer's cramp will be investigated. Two different programs will be offered: The first one will consist of a sensorimotor, the second one of an awareness training. All patients will benefit from video-based supervision with the aim to establish a practice-oriented therapeutic approach that will be available to all patients independently of their home location. The treatment effect will be measured primary with the patient-centered Canadian Occupational Performance Measure (COPM) and secondary with clinical scales to assess the clinical efficacy and everyday constraints. Writing will be assessed with a computer-based kinematic writing analysis. To evaluate the influence on the brain network, several functional magnetic resonance imaging (fMRI) evaluations will be performed. This project is of minimal risk without negative side effects from the training. The risks for the MRI experiment are equal to a non-contrast standard MRI investigation.

CONDITIONS

Official Title

Video-supervised Motor and Awareness Training in Writer's Cramp

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Right handed idiopathic writer's cramp according to standardized criteria (including simple and complex forms and any dystonic posture such as flexion, extension, pronation, supination)
  • Ability to participate in video-calls
Not Eligible

You will not qualify if you...

  • Presence of additional neurological or psychiatric diseases
  • Left-handed patients
  • Botulinum toxin treatment within the last 3 months or remaining weakness from last injection
  • Use of anticholinergics or sedating medication
  • Cardiac pacemaker, electronic or metal implants (for MRI exclusion)
  • Pregnancy or suspected pregnancy (for MRI exclusion)
  • Severe ametropia or anxiety in small rooms (for MRI exclusion)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Kiel University

Kiel, Schleswig-Holstein, Germany, 24105

Actively Recruiting

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Research Team

K

Kirsten E Zeuner, Prof. MD

CONTACT

A

Arne Knutzen, M.Sc. OT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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