Actively Recruiting

Age: 18Years +
All Genders
NCT06458504

Viral Infection of HSPC Impacts Hematopoiesis

Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-03-20

45

Participants Needed

1

Research Sites

70 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

We propose to demonstrate that HIV-1 and SARS-CoV-2 are capable of targeting long-lived HSPC with self-renewal capacities. These progenitors, thus transformed into host cells, can give rise to a durable source of infected cells with an impact on hematopoiesis.

CONDITIONS

Official Title

Viral Infection of HSPC Impacts Hematopoiesis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • HIV-positive patients with a negative or positive viral load
  • Managed at Ambroise Paré Hospital
  • Patients with a bone marrow biopsy or myelogram performed as part of their care
  • Healthy subjects without HIV who have had a bone marrow biopsy or myelogram for suspected hematological pathology
  • Managed at Ambroise Paré Hospital
Not Eligible

You will not qualify if you...

AI-Screening

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Trial Site Locations

Total: 1 location

1

Hematology and interne medicine department, Ambroise Paré hospital - APHP

Boulogne-Billancourt, France, 92100

Actively Recruiting

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Research Team

C

Claude CAPRON, MD, PhD

CONTACT

F

Fernando REAL, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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