Actively Recruiting

Phase Not Applicable
Age: 50Years +
All Genders
NCT07496255

Virtual Reality Cognitive Intervention for Critically Ill Delirium Survivors (VR-Cog)

Led by Indiana University · Updated on 2026-04-17

100

Participants Needed

1

Research Sites

69 weeks

Total Duration

On this page

Sponsors

I

Indiana University

Lead Sponsor

I

Indiana University Health

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to measure the feasibility, acceptability of virtual reality (VR) brain games and estimate their effect on memory, attention, and mood for ICU survivors. The VR program will be used at home through a headset and hand controls.

CONDITIONS

Official Title

Virtual Reality Cognitive Intervention for Critically Ill Delirium Survivors (VR-Cog)

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 50 years or older
  • English speaking
  • Admitted to the intensive care unit (ICU) with acute respiratory failure/invasive mechanical ventilation
  • Screening positive for delirium using Richmond Agitation Sedation Scale and Confusion Assessment Method for the ICU
Not Eligible

You will not qualify if you...

  • Acute neurologic injury such as stroke, traumatic brain injury, brain mass, intracranial hemorrhage, seizures, or central nervous system infection
  • Chronic cognitive or physical deficits preventing participation in study interventions or assessments
  • Chronic cognitive impairment including mild cognitive impairment or dementia identified by chart diagnosis, medications, or Informant Questionnaire on Cognitive Decline in the Elderly Score greater than 3.3
  • Severe, uncorrected vision or hearing impairment preventing participation
  • Admission with acute alcohol or drug intoxication or withdrawal
  • Severe, uncontrolled psychiatric disorders such as bipolar disorder or schizophrenia
  • History of severe vertigo, motion-induced sickness, headaches, light sensitivity, seizures, or prior intolerance of virtual reality
  • Receiving comfort care or not expected to survive hospitalization
  • Prisoners or unable to provide consent
  • Not expected to be discharged home, living more than 50 miles from recruitment site, or homeless

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

IU Health Methodist Hospital

Indianapolis, Indiana, United States, 46202

Actively Recruiting

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Research Team

S

Sikandar Khan, DO, MS

CONTACT

L

Lori Rawlings, RN, BSN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Virtual Reality Cognitive Intervention for Critically Ill Delirium Survivors (VR-Cog) | DecenTrialz