Virtual reality and hypnosis for anxiety and pain management in intensive care units: A prospective randomised trial among cardiac surgery patients.
Floriane Rousseaux, Nadia Dardenne, Paul B Massion...
https://pubmed.ncbi.nlm.nih.gov/34783683/Actively Recruiting
Led by University of Minho · Updated on 2026-05-13
51
Participants Needed
1
Research Sites
4 weeks
Total Duration
This trial investigates whether virtual reality VR helps improve thinking and memory skills in adults who have stayed in the intensive care unit ICU. It focuses on patients who required a breathing machine or had a long ICU stay and are at risk of memory or brain fog problems. The study compares the effects of immersive VR, tablet-based brain games, and standard care on cognitive recovery after critical illness. Participants are randomly assigned to one of three groups VR-based rehabilitation using a headset to play six brain-training games, tablet-based rehabilitation with the same games on a 2D device, or standard ICU care without digital cognitive training. Each digital therapy involves daily 12-minute sessions for up to seven days or until ICU discharge. The VR group uses a Meta Quest Pro device for immersive cognitive and motor exercises, while the tablet group uses a handheld device for the same tasks. During the study, participants complete memory and thinking tests at the start and about two weeks later. They also answer follow-up questions about their cognitive abilities for up to six months after hospital discharge. Safety is monitored continuously during therapy sessions, and researchers track outcomes like the Montreal Cognitive Assessment. Additional evaluations include muscle strength, post-trauma stress, quality of life, mood, anxiety, and any VR-related discomfort. The study lasts several months, with multiple follow-up visits to assess recovery.
CONDITIONS
Virtual Reality for Recovery After Intensive Care (PICS)
N
Nuno F. Rodrigues
I
Inês Oliveira
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University of Minho
Lead Sponsor
Universidade do Porto
Collaborating Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 7 days or until ICU discharge
Participants receive bedside rehabilitation sessions using either a virtual reality headset or a tablet to engage in cognitive and motor training. Sessions last approximately 12 minutes daily for up to 7 consecutive days or until ICU discharge. Participants in the standard care group receive conventional ICU rehabilitation without structured digital training.
Daily sessions for up to 7 days
Duration - Up to 6 months post-discharge
Participants are monitored after the intervention with scheduled assessments to evaluate cognitive, physical, and psychological recovery. These follow-ups occur up to 6 months post-discharge.
3 visits (approximately 15-22 days, 30-45 days, and 3 to 6 months post-discharge)
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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https://pubmed.ncbi.nlm.nih.gov/33614677/University of Minho
Lead Sponsor
Universidade do Porto
Collaborating Sponsor