Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05898789

Virtual Rehabilitation for Cancer Survivors

Led by University Health Network, Toronto · Updated on 2026-02-25

388

Participants Needed

1

Research Sites

177 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Pragmatic hybrid type 1 effectiveness-implementation (E-I) trial of a virtual cancer rehabilitation program: The study team will conduct a multi-center hybrid type I effectiveness-implementation study to examine the clinical effectiveness and implementation potential of an 8-week multidimensional virtual cancer rehabilitation intervention (CaRE@Home) for cancer survivors with identified cancer-related impairments on level of overall disability (primary outcome) and patient reported physical and social functioning, anxiety, work status, quality of life, and physiologic changes (secondary outcomes). The study team will conduct a multi-centre pragmatic randomized controlled trial (RCT) (Vancouver, Toronto, Saint John and St. John's) to evaluate effectiveness and using the CIFR, the study team will identify potential factors that may affect successful implementation and integration of CaRE@Home in different cancer settings.

CONDITIONS

Official Title

Virtual Rehabilitation for Cancer Survivors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosed with breast (stage 0-III), colorectal (stage I-III), head and neck (stage I-III), or lymphoma/lymphoproliferative disorder (excluding recurrent, refractory, progressive, or transplant cases)
  • Completed primary cancer treatment within the last 24 months
  • Eligible if on or completed systemic therapy with adjuvant/curative intent, including maintenance therapies like trastuzumab or immunotherapy
  • Sufficient English communication skills to complete the program and questionnaires
  • Willing to be randomized and participate in the intervention and assessments
  • Internet access available
  • Indication for cancer rehabilitation with WHO-DAS score greater than 5
Not Eligible

You will not qualify if you...

  • Impaired functional status preventing rehabilitation (PRFS greater than 3)
  • Signs of major depressive disorder (PHQ-9 score 20 or higher)
  • Diagnosed neurological disease significantly limiting cognitive function (e.g., Alzheimer's, dementia, severe brain injury)
  • Currently enrolled in another personalized supervised exercise or rehabilitation program
  • Medical conditions or injuries unsuitable for distance-based exercise without physician approval (e.g., high blood pressure, recent heart attack, unstable angina, spinal cord compression, recent deep vein thrombosis)

AI-Screening

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Trial Site Locations

Total: 1 location

1

Princess Margaret Cancer Centre

Toronto, Ontario, Canada, M5G 2N2

Actively Recruiting

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Research Team

C

charmaine silva, MSc

CONTACT

J

Jennifer Jones, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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