Actively Recruiting
Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms
Led by U: The Mind Company · Updated on 2026-01-27
30
Participants Needed
1
Research Sites
12 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study tests a new, non-invasive brain stimulation device called Sphere V3.0 to help improve movement problems in people with Parkinson's disease. The device delivers gentle electrical signals to the scalp using small electrodes placed on the head. Participants will use the device at home for 13 minutes each weekday (Monday through Friday) for 3 weeks, then be monitored for another 3 weeks without treatment. The entire study lasts 6 weeks and is conducted virtually through video calls and online assessments. The investigators will measure changes in Parkinson's symptoms using standard rating scales and video recordings of movement tasks like walking and hand tremor tests. Participants will also record videos of their movements at home using their smartphone or computer. The study includes 30 adults aged 18-80 who have been diagnosed with Parkinson's disease and have stable medication for at least 4 weeks. Participants must have reliable internet access and be able to follow the treatment schedule. The main goal is to see if this brain stimulation treatment can reduce motor symptoms like tremor, stiffness, and slowness of movement. The investigators will also check if any improvements last after treatment ends and monitor for any side effects. All participants receive the active device treatment - there is no placebo group. The device has been tested in over 250 people in previous studies with no serious adverse events reported
CONDITIONS
Official Title
Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18-80 years with confirmed diagnosis of Parkinson's Disease
- Hoehn & Yahr stages 1-4
- Stable medication regimen for 4 or more weeks prior to enrollment
- Reliable internet access and telehealth capability
- Ability to provide informed consent
- Willingness to comply with treatment protocols and follow-up procedures
You will not qualify if you...
- Metallic head or neck implants (excluding dental fillings)
- Pregnancy or nursing status
- Severe skin conditions at electrode placement sites
- History of epilepsy or seizures (unless technology specifically indicated)
- Recent stroke or traumatic brain injury within 6 months
- Severe cognitive impairment preventing treatment understanding
- Any neurological disorders contraindicating transcranial electrical stimulation
- Current participation in other clinical trials
- Inability to commit to full treatment and follow-up schedule
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
U LLC Headquarters
Cleveland, Ohio, United States, 44124
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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