Actively Recruiting
Vision Loss Impact on Navigation in Virtual Reality
Led by University of Rochester · Updated on 2026-01-09
40
Participants Needed
1
Research Sites
252 weeks
Total Duration
On this page
Sponsors
U
University of Rochester
Lead Sponsor
R
Rochester Institute of Technology
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving. Using a novel Virtual Reality (VR) program, the researchers will gather data on steering behavior in a variety of simulated naturalistic environments. Through the combined use of computer vision, deep learning, and gaze-contingent manipulations of the visual field, this work will test the central hypothesis that changes to visually guided steering behaviors in CB are a consequence of changes to the visual sampling and processing of task-related motion information (i.e., optic flow).
CONDITIONS
Official Title
Vision Loss Impact on Navigation in Virtual Reality
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Residents of the United States or Canada
- Age between 21 and 75 years
- Presence of one-sided stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter confirmed by MRI or CT scans
- Reliable visual field defects in both eyes (homonymous defects) measured by Humphrey or equivalent perimetry
- Willing, able, and competent to provide own informed consent
- Cognitively able to understand written and oral instructions in English
- Emmetropic or able to wear corrective contact lenses inside the virtual reality headset
- Normal or corrected-to-normal vision (for control group)
- Competent and responsible as determined by Principal Investigator (for control group)
- Normal cognitive abilities able to understand written and oral instructions in English (for control group)
You will not qualify if you...
- Never driven or earned a driver's license
- Past or present ocular disease interfering with visual acuity
- Best corrected visual acuity worse than 20/40 in either eye
- Sustained damage to dorsal lateral geniculate nucleus
- Presence of diffuse, whole-brain degenerative processes
- Brain damage interfering with outcome measures as determined by study staff
- History of traumatic brain injury
- Documented history of drug or alcohol abuse
- Diagnosis of cognitive or seizure disorders
- Diagnosis of one-sided attentional neglect
- Presence of vision loss from ocular diseases or disorders (for control group)
- Presence of visual field defect (for control group)
- Inability to wear corrective contact lenses inside virtual reality headset if needed (for control group)
- History of neurological disorders (for control group)
- Lack of competence or inability to perform visual testing as directed (for control group)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Rochester
Rochester, New York, United States, 14642
Actively Recruiting
Research Team
E
Evan Burr
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here