Actively Recruiting
Visual Involvement in Giant Cell Arteritis
Led by ASST Fatebenefratelli Sacco · Updated on 2024-07-15
762
Participants Needed
1
Research Sites
309 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This observational study aims to enhance the description of the different ways Giant Cell Arteritis (GCA) affects vision. The latest technology and knowledge are used to improve how we diagnose and predict patient outcomes. GCA is the most frequent vasculitis, an inflammation of vessels, in older adults. It involves large and medium-sized arteries and causes ischemic alterations such as stroke and blindness, through damage of extracranial arteries. The primary objective is to compare the frequency of the various ocular findings between the main alterations of arteritic and non-arteritic aetiology, such as Arteritic Anterior Ischemic Optic Neuropathy (A-AION) Vs. Non-Arteritic Anterior Ischemic Optic Neuropathy (NA-AION) or Central Retinal Artery Occlusion (CRAO) from GCA Vs. from other causes, through a comprehensive clinical and instrumental evaluation.
CONDITIONS
Official Title
Visual Involvement in Giant Cell Arteritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients older than 18 years with clinically suspected or confirmed Giant Cell Arteritis (GCA)
- Newly found visual involvement suspected or confirmed to be related to vasculitis
- Ability to provide valid consent to participate in the study
- Patients older than 18 years able to provide valid consent
- Newly diagnosed acute visual impairment with GCA-like features but without vasculitis-related cause
You will not qualify if you...
- Existing eye diseases that could affect best visual acuity or alter eye examination findings
- Active infections including viral, bacterial, fungal, or parasitic infections involving the eyes or surrounding areas
- Active or latent tuberculosis treated for less than 4 weeks
- HIV, hepatitis B, or hepatitis C infections affecting the eyes or orbital cavities
- Systemic inflammatory diseases not caused by GCA (unless in treatment-free remission)
- Any other condition deemed by investigators to prevent safe participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
ASST Fatebenefratelli-Sacco
Milan, Lombardy, Italy, 20157
Actively Recruiting
Research Team
E
Enrico Tombetti, Prof.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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