Study of Visual Problems in Giant Cell Arteritis Using Advanced Eye Tests Comparing Arteritic and Non-Arteritic Eye Conditions in Adults

What this Trial Is About

Researchers are investigating how Giant Cell Arteritis GCA, a condition causing inflammation in medium and large arteries, affects vision. This study focuses on comparing eye problems caused by arteritic and non-arteritic forms of visual impairment, such as Arteritic Anterior Ischemic Optic Neuropathy A-AION versus Non-Arteritic Anterior Ischemic Optic Neuropathy NA-AION, and Central Retinal Artery Occlusion CRAO due to GCA versus other causes. The goal is to improve diagnosis and prediction of patient outcomes using advanced eye imaging and clinical evaluations. Participants undergo various eye tests including fluorescein and indocyanine green angiography, high-resolution Optical Coherence Tomography OCT, and Angio-OCT at multiple time points baseline, 48-72 hours, 7 days, 4 weeks, 12 weeks, and 26 weeks. Blood samples are taken at baseline and during follow-up visits to help understand disease progression. Patients receive standard care based on international guidelines for GCA, and assessments include detailed eye exams and internal and immuno-rheumatological evaluations. During the study, participants will have regular evaluations of visual acuity, fundus examination, and visual field testing. Eye imaging and clinical data are collected and analyzed to identify patterns and changes in visual impairment linked to GCA. The study will track how vision changes over six months and assess the relationship between clinical findings and eye imaging results to better understand the diseases impact on vision over time.

Visual Involvement in Giant Cell Arteritis