Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT06911931

Visual Perception in Schizophrenia

Led by University of Rochester · Updated on 2025-11-12

84

Participants Needed

1

Research Sites

64 weeks

Total Duration

On this page

Sponsors

U

University of Rochester

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aims to identify novel markers of psychosis using electroencephalography (EEG).

CONDITIONS

Official Title

Visual Perception in Schizophrenia

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 65 years
  • Visual acuity of 20/32 or better using optical correction if needed
  • Ability to speak English well enough to complete assessments and consent
  • Diagnosis of schizophrenia, schizoaffective disorder, or schizophreniform disorder confirmed by DSM-5 criteria and SCID-5 interview
  • Diagnosis of bipolar disorder (type I, II, or unspecified) confirmed by DSM-5 criteria and SCID-5 interview
Not Eligible

You will not qualify if you...

  • Inability to understand study instructions or provide informed consent
  • Intellectual impairment with WRAT-5 score below 70
  • Active intoxication or substance use disorder in the past 3 months
  • High risk for suicidal acts or recent suicide attempt within 30 days
  • Recent severe violence or extreme agitation within prior 6 months
  • Current manic state
  • Head injury causing loss of consciousness over 10 minutes
  • Electroconvulsive therapy within past 8 weeks
  • Diagnosed neurological conditions including tumors, stroke, brain injury, seizure disorders, or pervasive developmental disorders
  • Eye problems such as lazy eye, squint, or other ocular pathology
  • For healthy controls: any lifetime psychotic disorder, psychiatric hospitalization history, recent psychotropic medication use, or first-degree relative with schizophrenia spectrum or bipolar disorder
  • For case-match controls: lifetime psychotic disorder, recurrent or current depressive episodes, persistent psychotic symptoms, psychiatric hospitalization history, recent psychotropic medication use, or first-degree relative with schizophrenia spectrum or bipolar disorder
  • For bipolar subjects: persistent threshold psychotic symptoms

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Rochester

Rochester, New York, United States, 14642

Actively Recruiting

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Research Team

E

Edmund Lalor, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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Visual Perception in Schizophrenia | DecenTrialz