Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07105358

Visual Plasticity Following Brain Lesions

Led by Georgetown University · Updated on 2025-08-05

30

Participants Needed

1

Research Sites

154 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.

CONDITIONS

Official Title

Visual Plasticity Following Brain Lesions

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants must be at least 18 years old.
  • Must be able to provide informed consent and comply with study procedures.
  • Must have unilateral or bilateral focal brain damage causing vision loss.
  • Must be at least three months post-stroke or traumatic brain injury, or have a stable brain tumor within the past year.
  • Healthy volunteers must be age-matched and meet the age and consent requirements.
Not Eligible

You will not qualify if you...

  • Severe central nervous system diseases or disorders unrelated to the focal lesion that could affect study results.
  • Severe mental health challenges or drug/alcohol abuse in the past 6 months as defined by DSM-5.
  • Vision loss caused by an ocular disease or disorder.
  • For healthy volunteers, any CNS diseases or psychiatric disorders (e.g., epilepsy, schizophrenia).
  • Previous head injury for healthy volunteers.
  • Present or past drug or alcohol abuse within the past 6 months for healthy volunteers.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Georgetown University Medical Center

Washington D.C., District of Columbia, United States, 20057

Actively Recruiting

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Research Team

T

Tina Liu, PhD

CONTACT

K

Kyungji Moon, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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Visual Plasticity Following Brain Lesions | DecenTrialz