Actively Recruiting

Phase 4
Age: 18Years +
All Genders
Healthy Volunteers
NCT06440473

Visualization of Topical Zoryve vs. Vehicle Using Line Field Optical Coherence Tomography in Healthy Skin

Led by Rao Dermatology · Updated on 2024-06-03

3

Participants Needed

1

Research Sites

8 weeks

Total Duration

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AI-Summary

What this Trial Is About

The goal of this study is to visualize the deposition of topical 0.3% roflumilast (Zoryve) compared to vehicle using Line-Field Optical Coherence Tomography (LC-OCT) in vivo in healthy skin. We hypothesize that the application of topical 0.3% roflumilast (Zoryve) will result in distinct patterns of deposition within the epidermal and dermal layers compared to the vehicle. Specifically, we anticipate observing deeper penetration and more uniform distribution of roflumilast within the skin layers, indicative of enhanced efficacy, as visualized by LC-OCT imaging.

CONDITIONS

Official Title

Visualization of Topical Zoryve vs. Vehicle Using Line Field Optical Coherence Tomography in Healthy Skin

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy subjects over 18 years of age
  • Subjects must provide written informed consent
  • Participants recruited from outpatient dermatology clinic, Rao Dermatology
Not Eligible

You will not qualify if you...

  • History of immune-mediated skin conditions
  • Received systemic therapy within the last 60 days
  • Use of topical therapy within 7 days prior to enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Rao Dermatology

Atlantic Highlands, New Jersey, United States, 07716

Actively Recruiting

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Research Team

B

Bassem Rafiq, BS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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