Actively Recruiting

Phase 2
Phase 3
Age: 18Years +
All Genders
NCT07112196

Visugromab in Cachexia International Trial

Led by CatalYm GmbH · Updated on 2026-04-23

518

Participants Needed

7

Research Sites

241 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A study of how well and safely a new drug called visugromab works in people with certain kinds of cancer (including lung and bowel cancer) and unintended weight loss known as cachexia. The main questions it aims to answer are: * Does visugromab help participants put weight back on and have a better appetite? * Does visugromab help participants move more and better? * What medical problems do participants have when taking visugromab? Researchers will compare visugromab to a placebo (a look-alike substance that contains no drug). Participants will visit the hospital or clinic once every 4 weeks to receive visugromab or placebo via a drip into a vein and to undergo checkups and tests.

CONDITIONS

Official Title

Visugromab in Cachexia International Trial

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Weight loss
  • Advanced cancer
Not Eligible

You will not qualify if you...

  • Participation in another interventional clinical trial, receipt of any investigational therapy or use of any investigational device within 4 weeks prior to screening and between screening and the first dose of investigational product

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 7 locations

1

Mid Florida Hematology and Oncology Centers

Orange City, Florida, United States, 32763

Actively Recruiting

2

Specialized Hospital for Active Treatment in Oncology

Haskovo, Bulgaria, 6300

Actively Recruiting

3

Léon Bérard Center (Centre Léon Bérard)

Lyon, France, 69008

Actively Recruiting

4

Oslo University Hospital

Oslo, Norway, 0372

Actively Recruiting

5

University Hospital of A Coruña (Hospital Universitario de A Coruña)

A Coruña, Spain, 15006

Actively Recruiting

6

Cantonal Hospital St. Gallen (Kantonsspital St. Gallen)

Sankt Gallen, Switzerland, 9000

Actively Recruiting

7

University Hospital of Zurich (Universitätsspital Zürich)

Zurich, Switzerland, 8006

Actively Recruiting

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Research Team

T

Trial Director

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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Visugromab in Cachexia International Trial | DecenTrialz