Vitamin D to Prevent Recurrence of Pre-eclampsia in Pregnant Women A Randomized Controlled Study for Women With Previous Pre-eclampsia History

What this Trial Is About

This clinical trial investigates whether giving vitamin D supplements to pregnant women who had pre-eclampsia in a previous pregnancy can help prevent the condition from returning. The study aims to find out if vitamin D reduces the chance of recurrent pre-eclampsia in this group of women. Pregnant women attending the antenatal clinic at Nishtar Hospital Multan are invited to participate in this research. Participants will be randomly assigned to one of two groups. One group will take 4,000 IU of oral vitamin D daily until 36 weeks of pregnancy. The other group will receive a placebo pill that looks, tastes, and feels the same but contains no vitamin D. Each woman will visit the clinic every two weeks during the study period. During each visit, blood pressure will be checked, and if it reaches 14090 mmHg or higher, a urine test will be done to check for protein, which helps identify pre-eclampsia. If pre-eclampsia is diagnosed, standard care will be provided and recorded. The main outcome is to compare how many women in each group develop recurrent pre-eclampsia by 36 completed weeks of pregnancy.

Vitamin D for Preventing Recurrent Preeclampsia in Pregnant Women