Actively Recruiting

Phase 2
Phase 3
Age: 10Years - 75Years
All Genders
Healthy Volunteers
NCT06768840

Vitiligo, New Treatment and Serum s100B

Led by South Valley University · Updated on 2025-01-10

50

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

vitiligo is an autoimmune depigmenting skin disorder characterized by milky white macules or patches, with 2% worldwide prevalence. Vitiligo has unexpected course that significantly influences on patient's quality of life and self-esteem. Multiple medications have been introduced for vitiligo treatment, in this study we work on one of systemic JAK inhibitors

CONDITIONS

Official Title

Vitiligo, New Treatment and Serum s100B

Who Can Participate

Age: 10Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Active generalized vitiligo with more than 5% body surface area affected, excluding hands and feet
  • No systemic vitiligo treatment in the last 3 months
  • No topical vitiligo treatment in the last 4 weeks
  • Age between 10 and 75 years
Not Eligible

You will not qualify if you...

  • Acrofacial, acral, segmental, or mucosal vitiligo
  • Use of other immunosuppressive agents
  • Other skin conditions affecting evaluation such as psoriasis, lupus, or alopecia areata
  • Systemic diseases affecting s100B levels like subarachnoid hemorrhage, Alzheimer disease, or inflammatory diseases
  • Other dermatological diseases affecting s100B like malignant melanoma
  • Immunocompromised status or uncontrolled arterial hypertension
  • Serious infections (viral, bacterial, fungal, parasitic), anemia, or history of thromboembolic events
  • Cardiovascular, respiratory, hepatic, gastrointestinal, endocrine, hematological, lymphoproliferative, neurological, neuropsychiatric disorders, or other serious unstable illnesses
  • Pregnancy or lactation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Qena university hospital, Qena faculty of medicine

Qina, Egypt

Actively Recruiting

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Research Team

E

Eman A Osman, bachelor

CONTACT

H

Hassan mo farid, bachelor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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