Actively Recruiting

Phase Not Applicable
Age: 40Years - 75Years
MALE
NCT06424912

Vivifi's Treatment, BPH Treatment Via Vasculature Anastomosis

Led by Vivifi Medical · Updated on 2025-04-11

20

Participants Needed

1

Research Sites

84 weeks

Total Duration

On this page

Sponsors

V

Vivifi Medical

Lead Sponsor

R

RQM+

Collaborating Sponsor

AI-Summary

What this Trial Is About

The study objective is to evaluate the safety and feasibility of the Vivifi's Treatment. The Vivifi's Treatment presents an innovative approach for addressing benign prostatic hyperplasia (BPH) as well as clinical/subclinical varicoceles in men. The scientific rationale for conducting this study is to assess the safety and feasibility of the Vivifi's Treatment (a surgical procedure) as a therapeutic intervention for patients with BPH.

CONDITIONS

Official Title

Vivifi's Treatment, BPH Treatment Via Vasculature Anastomosis

Who Can Participate

Age: 40Years - 75Years
MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Male 40-75 years of age
  • Diagnosed with benign prostatic hyperplasia (BPH)
  • Prostate volume between 30 and 120 cc measured by transrectal ultrasound
  • Signed the study informed consent form
  • Lower urinary tract symptoms with International Prostate Symptoms Score (IPSS) greater than 12
  • Presence of clinical varicocele, preferably grade II or III (Dubin & Amelar)
Not Eligible

You will not qualify if you...

  • Prior surgeries or impairment related to spermatic vein or pampiniform plexus, or vasectomy
  • Previous invasive prostate interventions like TURP, laser, ablation, or prostate artery embolization
  • Prostate with large intravesical median lobe
  • Sub-clinical varicocele
  • Post-void residual volume greater than 110 ml
  • IPSS greater than 24
  • History of chronic prostatitis
  • History of urinary retention with catheterization in the past 30 days
  • Major neurological conditions such as Alzheimer's, Parkinson's, multiple sclerosis, ALS, or spinal cord injury
  • Unable to undergo general anesthesia
  • Use of blood thinners or coagulation issues like TTP
  • Prior pelvic floor surgery or conditions such as inguinal hernia or mesh
  • History of genitourinary cancer not considered cured (no evidence of cancer within 5 years)
  • Inability to provide informed consent or comply with follow-up
  • Currently participating in other investigational studies without sponsor approval

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital Paitilla

Panama City, Provincia de Panamá, Panama

Actively Recruiting

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Research Team

Y

Yunlong Zhang, Master of Science

CONTACT

T

Tushar Sharma, CEO of Vivifi (Study sponsor)

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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