Actively Recruiting
In Vivo Study on the Material Properties of iRoot SP and nRoot SP Root Canal Sealers
Led by The Dental Hospital of Zhejiang University School of Medicine · Updated on 2026-04-15
160
Participants Needed
1
Research Sites
109 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A randomized controlled trial was conducted to compare the treatment efficacy of iRoot SP and nRoot SP Root Canal Sealer Materials in patients with chronic apical periodontitis.
CONDITIONS
Official Title
In Vivo Study on the Material Properties of iRoot SP and nRoot SP Root Canal Sealers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age ≥ 18 years.
- Diagnosis of apical periodontitis conforming to the diagnostic criteria in Endodontics.
- The affected tooth is deemed restorable upon evaluation, with non-vital pulp requiring extirpation.
- The affected tooth is a single tooth with a fully developed apical foramen.
- No root resorption and no significant morphological variation of the root canal.
- The affected tooth is undergoing primary root canal treatment.
- Periapical radiolucency with a diameter of 1-5 mm and no peripheral sclerotic border observed on preoperative radiographs.
- Patient is in normal mental state, conscious, and capable of normal communication.
- Patient has provided informed consent.
You will not qualify if you...
- Patients with alveolar bone loss exceeding one-third of the root length.
- Affected teeth with root fracture, root canal obstruction, calcification, or root surface caries.
- Patients with severe systemic diseases (e.g., osteoporosis, mental disorders, hepatic or renal insufficiency).
- Patients who have taken analgesics, immunosuppressants, or antibiotics within one week prior to enrollment.
- Patients with concurrent periapical cysts, oral tumors, or other oral diseases.
- Pregnant or lactating patients.
- Patients with dental phobia, severe gag reflex, limited mouth opening, or poor compliance.
- Patients with a known allergy to the root canal sealer materials.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
School of Stomatology, The Affiliated Stomatology Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
Research Team
T
Tu Yan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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