Actively Recruiting
Volumetric Dimensional Changes After Surgical Pontic Site Development Procedures With Connective Tissue Graft or Collagen Matrix
Led by University of Bern · Updated on 2026-02-18
38
Participants Needed
1
Research Sites
239 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this research project is to compare two surgical procedures to improve soft tissue volume. Both procedures have already been validated, but despite their great clinical relevance, little data exists in the literature. With this study, the investigators aim to evaluate volumetric changes of connective tissue graft versus biomaterial (membrane). In addition, further clinical measurements will be taken and patient satisfaction will be assessed.
CONDITIONS
Official Title
Volumetric Dimensional Changes After Surgical Pontic Site Development Procedures With Connective Tissue Graft or Collagen Matrix
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent
- Age 18 years or older
- Willingness to participate in the study
- Single tooth gap or extended missing tooth area in the lower or back jaw with soft tissue deficiency
- Tooth gap of at least 8 mm
- Presence of natural or artificial opposing teeth
- Sufficient vertical space (7 mm) for implant restoration
- Bounded by natural and periodontally stable teeth
- Treatment plan includes tooth replacement with implant or fixed dental prosthesis
You will not qualify if you...
- Physical or mental disorders preventing good oral hygiene, informed consent, or study compliance
- Severe teeth grinding, clenching, or oro-facial pain
- Uncontrolled diabetes with HbA1c over 7.0
- Significant other diseases (kidney failure, liver problems, heart disease, etc.)
- Active oral or systemic infections
- Current or past chemo- or radiotherapy in head and neck
- Severe blood disorders
- Diseases or medications affecting wound healing
- Pregnancy or breastfeeding
- Contraindications to device use, including allergies to porcine material or collagen
- Vulnerable individuals
- Known or suspected non-compliance
- Drug or alcohol abuse
- Inability to follow study procedures due to language or psychological issues
- Participation in other drug or device studies within 30 days
- Enrollment of the principal investigator or related persons
AI-Screening
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Trial Site Locations
Total: 1 location
1
University of Bern
Bern, Switzerland, 3010
Actively Recruiting
Research Team
M
Manrique Fonseca, DDS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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