Actively Recruiting

Phase Not Applicable
All Genders
NCT06886451

Vomiting Prevention in Children With Cancer

Led by The Hospital for Sick Children · Updated on 2026-03-05

1332

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this single arm trial is to learn if a machine learning (ML) model predicting the risk of vomiting within the next 96 hours will impact vomiting outcomes in inpatient cancer pediatric patients. The main questions it aims to answer are whether an ML model predicting the risk of vomiting within the next 96 hours will: Primary 1\. Reduce the proportion with any vomiting within the 96-hour window Secondary 1. Reduce the number of vomiting episodes 2. Increase the proportion receiving care pathway-consistent care 3. Impact on number of administrations and costs of antiemetic medications Newly admitted participants will have a ML model predict the risk of vomiting within the next 96 hours according to their medical admission information. The prediction will be made at 8:30 AM following admission. Pharmacists will be charged with bringing information about patients' vomiting risk to the attention of the medical team and implementing interventions.

CONDITIONS

Official Title

Vomiting Prevention in Children With Cancer

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • All pediatric patients admitted to the oncology service at SickKids
Not Eligible

You will not qualify if you...

  • Pediatric patients admitted to the oncology service at SickKids that are discharged prior to prediction time

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

The Hospital for Sick Children

Toronto, Ontario, Canada, M5G1X8

Actively Recruiting

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Research Team

L

Lillian Sung, MD, PhD

CONTACT

A

Agata Wolochacz, BMSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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Vomiting Prevention in Children With Cancer | DecenTrialz