Actively Recruiting
VR and Orthoses for Rehabilitation in Multiple Sclerosis
Led by Azienda Usl di Bologna · Updated on 2026-03-30
12
Participants Needed
2
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This non-drug, non-medical device, interventional study explores the feasibility of integrating virtual reality (VR) with wearable sensors to support gait training using a passive orthosis in individuals with multiple sclerosis (MS). The aim is to determine whether this approach can enhance clinical gait assessment and facilitate orthosis adaptation by replicating real-life scenarios within a safe and controlled environment. The virtual environment, accessed through a head-mounted display, will be delivered via a custom simulator incorporating standardized gait tasks embedded in everyday settings. This system is designed to minimize the artificial influence of clinical settings on walking performance, while providing clinicians with objective gait data for more comprehensive evaluation.
CONDITIONS
Official Title
VR and Orthoses for Rehabilitation in Multiple Sclerosis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Confirmed diagnosis of multiple sclerosis
- Age between 18 and 65 years
- Both sexes
- Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) score above 100
- Expanded Disability Status Scale (EDSS) between 3 and 6 inclusive
- Berg Balance Scale (BBS) score of 46 or higher
- Indicated for use of the Exoband orthosis for gait support
- Modified Fatigue Impact Scale (MFIS) physical subscale score of 20 or less
- Signed informed consent
You will not qualify if you...
- Severe or current visual or auditory impairments
- Multiple sclerosis relapses within the last 3 months
- Severe anxiety or depression
- Severe spasticity in lower limbs or fixed distal tendon contractures
- Motion sickness symptoms triggered by virtual reality
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
IRCCS Istituto delle Scienze Neurologiche di Bologna - AUSL of Bologna
Bologna, Bologna, Italy, 40139
Not Yet Recruiting
2
IRCCS Istituto delle Scienze Neurologiche di Bologna - AUSL of Bologna
Bologna, BO, Italy, 40139
Actively Recruiting
Research Team
K
Kevin Marcaccini
CONTACT
L
Loredana Sabattini
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SCREENING
Number of Arms
1
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