Actively Recruiting

Phase 4
All Genders
NCT06873321

VTE Incidence After Rivaroxaban + Aspirin or SAPT After Lower-limb Revascularization

Led by Science Valley Research Institute · Updated on 2025-03-12

100

Participants Needed

1

Research Sites

74 weeks

Total Duration

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AI-Summary

What this Trial Is About

Venous thromboembolism (VTE) has a high prevalence in patients with multiple comorbidities undergoing complex surgical procedures. Sometimes, extended prophylaxis for VTE with KLMWH or direct oral anticoagulants (DOACs) is necessary. Currently, there is no consensus in the literature regarding the use of DOACs for extended VTE prophylaxis in patients undergoing lower limb revascularization (LLR). Objective: To evaluate the use of DOACs (already approved to reduce MACE and MALE) in VTE prophylaxis in patients undergoing LLR.

CONDITIONS

Official Title

VTE Incidence After Rivaroxaban + Aspirin or SAPT After Lower-limb Revascularization

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be adults of any age and gender
  • Have critical limb ischemia with a planned lower limb revascularization by angioplasty or bypass surgery at HC/EBSERH-UFPE
  • Sign the informed consent form
Not Eligible

You will not qualify if you...

  • Have a symptomatic venous thromboembolism event during hospitalization requiring full anticoagulation
  • Have any contraindications to rivaroxaban
  • Do not return for the 30-day postoperative follow-up visit

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital das Clínicas, Federal University of Pernambuco

Pernambuco, Pernambuco, Brazil, 50740-900

Actively Recruiting

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Research Team

G

Gabriela Oliveira Buril, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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