Actively Recruiting

Phase Not Applicable
Age: 18Years - 40Years
FEMALE
ID06981611

Vulvodynia Intervention (VI): the Effect of Multimodal Treatment for Provoked Vulvodynia

Led by Karlstad University · Updated on 2025-05-21

50

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

K

Karlstad University

Lead Sponsor

R

Region Stockholm

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating a multimodal treatment for provoked vulvodynia, a condition causing chronic vulvar pain. The study aims to assess the feasibility and acceptability of this treatment, its effects on pain and psychosexual health, and how patients, clinicians, and healthcare stakeholders perceive the treatment and its implementation. The project uses a mixed-methods design including both effectiveness and qualitative evaluations across multiple healthcare units. The treatment involves about 11 individual sessions over four months, combining physiological and psychosocial approaches to encourage goal-directed behavior change. Sessions are mostly held via digital video meetings, with some in-person visits, and partners may participate in two sessions. Participants are randomized to a 4, 5, or 6 week baseline period before starting treatment, and a follow-up session occurs three months after treatment ends. Repeated assessments, including pain measurements twice a week, are collected throughout the baseline and treatment periods. Participants undergo a gynecological exam and psychological assessment to confirm suitability, then complete questionnaires on pain, physical tension, sexual and relational health, and treatment experience. They may also be interviewed about their treatment and intimacy experiences. Researchers track changes in pain during touch or insertion, sexual function, pelvic floor tension, and psychological symptoms before, during, and up to six months after treatment. Safety and assessment data are collected through digital tools and interviews, with the overall study lasting about 25 weeks per participant.

CONDITIONS

Brief Title

Vulvodynia Intervention: the Effect of Multimodal Treatment for Provoked Vulvodynia

Who Can Participate

Age: 18Years - 40Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female biological sex
  • Age between 18 and 40 years
  • Diagnosis of provoked vulvodynia
Not Eligible

You will not qualify if you...

  • Severe psychological issues requiring priority before vulvodynia treatment (e.g., substance abuse, psychosis)
  • Currently pregnant
  • Childbirth within the last year
  • Post-traumatic stress disorder related to sexual trauma
  • Insufficient mastery of the Swedish language
  • No experience of vaginal sex, as vaginismus might be suspected

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or digital)

Baseline Period

Duration - 4 to 6 weeks

Participants undergo a randomized baseline period of 4, 5, or 6 weeks during which they complete self-assessment questionnaires twice a week to measure pain and other key variables.

Twice-weekly self-assessments using the m-Path app

Outpatient Treatment

Duration - Approximately 19 weeks

Participants receive approximately 11 treatment sessions consisting of physiological and psychosocial components focused on goal-directed behavioral change. The first five sessions are weekly, and the last six are biweekly. Sessions are conducted via digital video meetings and in-person at the healthcare facilities, with an option to involve a partner in two sessions.

11 treatment sessions (combination of weekly and biweekly visits) plus twice-weekly self-assessments using the m-Path app

Follow-up

Duration - 3 months after treatment ends

Participants complete a follow-up session three months after the end of treatment to assess outcomes and treatment effects.

1 follow-up visit plus web-based self-assessments before and after treatment and at 6 months follow-up

Trial Site Locations

Total: 1 location

1

Karlstad University

Karlstad, Sweden

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

2

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