Actively Recruiting
Washed Microbiota Transplantation for Attention-deficit/Hyperactivity Disorder
Led by The Second Hospital of Nanjing Medical University · Updated on 2025-09-05
50
Participants Needed
2
Research Sites
165 weeks
Total Duration
On this page
Sponsors
T
The Second Hospital of Nanjing Medical University
Lead Sponsor
N
Nanjing Medical University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder characterized by inattention and hyperactivity-impulsivity. ADHD is often accompanied by oppositional defiant disorder and sleep disturbance, and can increase the risk of other psychiatric disorders, functional impairment in academic and occupational performance. Recently, gut microbiota has been implicated in the ADHD via gut-brain axis. In this study, investigators aimed to evaluate the efficacy of WMT for core ADHD symptoms and its comorbidities using specialized questionnaires for ADHD and investigate the underlying mechanism.
CONDITIONS
Official Title
Washed Microbiota Transplantation for Attention-deficit/Hyperactivity Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children diagnosed with ADHD according to the Diagnostic And Statistical Manual of Mental Disorders Fifth Edition
- Aged between 3 and 17 years
- Receiving stable ADHD treatments for at least 1 month before WMT
- No use of antibiotics or probiotics affecting gut microbiota in the 3 months before WMT
You will not qualify if you...
- Unable to understand questionnaires or provide informed consent by guardian
- Diagnosed with single-gene disorder, psychosis, central nervous system diseases, or gastrointestinal diseases such as ulcerative colitis, Crohn's disease, celiac disease, or eosinophilic esophagitis
- Having severe comorbidities including heart or lung failure, severe liver or kidney disease, or cancer
- Having other life-threatening disorders requiring emergency treatment
- Unable to tolerate colonoscopy or anesthesia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Department of Microbiota Medicine & Medical Centre for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China
Actively Recruiting
2
SIR RUN RUN hospital of Nanjing Medical University
Nanjing, Jiangsu, China
Actively Recruiting
Research Team
F
Faming Zhang, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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