Actively Recruiting

Phase 1
Age: 6Years - 17Years
All Genders
Healthy Volunteers
NCT03764748

Washed Microbiota Transplantation for Tourette's Syndrome

Led by The Second Hospital of Nanjing Medical University · Updated on 2024-08-19

30

Participants Needed

2

Research Sites

184 weeks

Total Duration

On this page

Sponsors

T

The Second Hospital of Nanjing Medical University

Lead Sponsor

N

Nanjing Medical University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aimed to evaluate the efficacy of washed microbiota transplantation in the treatment of Tourette's syndrome (TS).

CONDITIONS

Official Title

Washed Microbiota Transplantation for Tourette's Syndrome

Who Can Participate

Age: 6Years - 17Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 6 to 17 years (inclusive)
  • Diagnosed with Tourette's Syndrome based on DSM-5 criteria
  • Yale Global Tic Severity Scale-Total Tic Score (YGTSS-TTS) of at least 20 at screening and baseline
  • Undergoing washed microbiota transplantation (WMT) treatment
Not Eligible

You will not qualify if you...

  • Having brain diseases such as tumors, injuries, or cerebrovascular disease
  • Having severe diseases including cancers, organ failure, or heart diseases
  • Exhibiting stereotypy linked to autism spectrum disorder
  • Diagnosed with psychiatric disorders like bipolar disorder, schizophrenia, or major depression
  • Having clinically significant obsessive-compulsive disorder as the main cause of impairment
  • Using medications that affect gut microbiota such as antibiotics or probiotics within three months before WMT
  • Having neurological disorders other than Tourette's Syndrome that could affect tic evaluation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 2 locations

1

Department of Microbiota Medicine & Medical Centre for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University

Nanjing, Jiangsu, China, 210011

Actively Recruiting

2

SIR RUN RUN hospital of Nanjing Medical University

Nanjing, Jiangsu, China, 210011

Actively Recruiting

Loading map...

Research Team

F

Faming Zhang, MD; PHD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here