Hernias: inguinal and incisional.
Andrew Kingsnorth, Karl LeBlanc
https://pubmed.ncbi.nlm.nih.gov/14615114/Actively Recruiting
Led by Northwestern University · Updated on 2026-06-26
380
Participants Needed
1
Research Sites
52 weeks
Total Duration
Researchers are studying the best way to manage small hidden hernias found during minimally invasive surgery to repair a known hernia on one side of the groin. This trial compares two approaches repairing the hidden hernia immediately during surgery versus monitoring it over time without repair. The purpose is to determine if immediate repair is as safe and effective as watchful waiting, helping doctors and patients make better treatment decisions. Participants who have a hidden hernia discovered during surgery will be randomly assigned to one of two groups. One group will have the hidden hernia repaired right away using a surgical mesh technique following repair of their known hernia. The other group will have only the known hernia repaired, with the hidden hernia left alone and monitored. The study tracks outcomes at 30 days, 1 year, and 2 years after surgery. During the study, participants will be followed up to assess recovery, quality of life, hernia symptoms, complications, and whether the hidden hernia later requires surgery. Researchers will measure quality of life 30 days after surgery and monitor wound complications, pain, readmissions, and hernia recurrence over two years. The study also evaluates opioid use and cost effectiveness. Participants can expect follow-up visits to gather health information and track their progress over time.
CONDITIONS
Watchful Waiting Versus Immediate Repair for Occult Contralateral Inguinal Hernias.
M
Megan S Melland-Smith, MD
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Northwestern University
Lead Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Immediate surgical repair of occult contralateral hernia | Repair symptomatic side only, monitor occult hernia (watchful waiting) |
|---|---|---|
| What is it? | Surgical repair of both the symptomatic and occult contralateral inguinal hernia during a single operation, using TAPP (transabdominal preperitoneal) repair with mesh. | Only the symptomatic hernia is repaired during the initial operation; the occult hernia on the opposite side is left unrepaired and monitored for symptoms or complications. |
| Role in the trial | Test arm assessing whether immediate repair of incidental occult hernia improves quality of life and reduces future hernia-related complications. | Comparator arm evaluating the outcomes of observing occult hernias and intervening only if symptoms or complications develop. |
| Primary use | Treat both symptomatic and asymptomatic (occult) inguinal hernias in a single surgery to potentially avoid future symptoms, complications, or need for additional surgery. | Resolve symptoms from the known hernia and monitor the occult hernia, avoiding unnecessary intervention unless it becomes symptomatic or causes complications. |
| How is it given or performed? | Performed during laparoscopic TAPP repair by placing mesh on both hernia sites at the time of surgery for the symptomatic hernia. | Only the symptomatic hernia is repaired using TAPP and mesh during surgery; the occult hernia is left untreated but is monitored after surgery. |
| Evidence status | Existing studies and systematic reviews have evaluated immediate repair of occult hernias; some evidence suggests it may reduce future hernia-related events and need for subsequent surgery, but further high-quality data are needed. | Randomized trials in minimally symptomatic or occult inguinal hernias show that watchful waiting is generally safe, with a low risk of emergency surgery or acute complications, supporting its use as a reasonable option. |
| Important limitations | Immediate repair may increase the risk of surgical complications, such as chronic pain or wound issues, and requires longer operative time. Existing evidence does not establish clear superiority for all patients. | Some patients managed with watchful waiting may later require another surgery if the occult hernia becomes symptomatic, leading to possible repeat anesthesia and added healthcare costs. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Single surgery event with follow-up
Participants undergo minimally invasive surgery to repair their known hernia. If a hidden hernia is found, they are randomly assigned to either immediate repair of the hidden hernia or watchful waiting without repair.
Follow-up visits at 30 days, 1 year, and 2 years after surgery
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Lead Sponsor