Actively Recruiting

Phase Not Applicable
Age: 45Years - 80Years
All Genders
Healthy Volunteers
NCT06496958

Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance

Led by Evergreen General Hospital, Taiwan · Updated on 2024-11-05

400

Participants Needed

2

Research Sites

108 weeks

Total Duration

On this page

Sponsors

E

Evergreen General Hospital, Taiwan

Lead Sponsor

E

E-Da Dachange Hospital, Kaohsiung, Taiwan

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this trial is to evaluate whether water exchange colonoscopy and CO2-insufflation colonoscopy with an abdominal compression device (Maxbelt me3 type, Nippon Sigmax Co., Tokyo, Japan) can achieve a significantly lower proportion of patients requiring manual abdominal pressure during colonoscopic insertion compared with CO2 insufflation alone.

CONDITIONS

Official Title

Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance

Who Can Participate

Age: 45Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 45-80 years having an average risk for colorectal cancer who plan to undergo sedated outpatient colonoscopy for screening, surveillance, and those who have received a positive fecal immunochemical test result
Not Eligible

You will not qualify if you...

  • Patients with hereditary colorectal cancer syndrome, including familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer (Lynch syndrome)
  • Patients with serrated polyposis syndrome
  • Patients with known or suspected inflammatory bowel disease
  • Patients with a history of colorectal cancer or other intra-abdominal malignancy
  • Patients with a history of colorectal resection
  • Patients with a history of abdominal aortic aneurysm, cirrhosis, ascites, or other severe comorbid illnesses
  • Patients with recent wounds or skin rash on the anterior abdominal wall and back
  • Patients with known ventral hernia
  • Patients with unsedated procedure
  • Patients with planned bidirectional endoscopy
  • Patients with body mass index >35 kg/m2
  • Patients with waist circumference <55 cm or >105 cm
  • Patients with known or suspected gastroparesis
  • Patients with planned therapeutic procedures (e.g., hemostasis, removal of a large polyp)
  • Patients with mental retardation
  • Pregnant women or those planning pregnancy
  • Patients unwilling to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

E-Da Dachang Hospital

Kaohsiung City, Taiwan, 807

Actively Recruiting

2

Evergreen General Hospital

Taoyuan, Taiwan, 320

Actively Recruiting

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Research Team

C

Chi-Liang Cheng, MD

CONTACT

J

Jen-Hao Yeh, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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Water Exchange and CO2 Insufflation With Abdominal Compression Device to Reduce Manual Assistance | DecenTrialz