Actively Recruiting
Wavelength Intervention for Nearsighted Kids
Led by University of Alabama at Birmingham · Updated on 2025-10-08
80
Participants Needed
1
Research Sites
120 weeks
Total Duration
On this page
Sponsors
U
University of Alabama at Birmingham
Lead Sponsor
N
National Eye Institute (NEI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn if daily brief periods of specialized soft contact lens wear work to slow the progression of nearsightedness in children. Additionally, the study will learn about the compliance and safety of specialized soft contact lens wear in children. The main questions it aims to answer are: Does wearing specialized soft contact lenses daily slow myopia progression and axial elongation? What visual/ocular problems do participants have when wearing specialized soft contact lenses? Researchers will compare two soft contact lenses to see if specialized soft contact lens wear works to treat childhood myopia progression. Participants will 1. Wear either a single type of soft contact lens or two types of soft contact lenses at alternate times daily full time in both eyes for one year. 2. Visit the clinic at 2 weeks, 1 month, 3 months, 6 months, and 12 months for checkups and tests 3. Keep a diary of the lens-wearing times.
CONDITIONS
Official Title
Wavelength Intervention for Nearsighted Kids
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Spherical component of refractive error in primary meridian between -0.75 and -5.00 diopters
- Less than 1.00 diopter of astigmatism or anisometropia
- History of soft contact lens wear for at least one week
- Best-corrected visual acuity of 20/25 (or +0.10 logMAR) or better in each eye
- Willingness to wear the lenses at least 10 hours per day, six days a week for the study duration
You will not qualify if you...
- Use of myopia control treatments within the past six months
- History of premature birth (less than 3.3 pounds) or preterm birth (earlier than 30 weeks)
- Current use of systemic or eye medications that may affect contact lens wear, tear health, refractive state, pupil response, or focusing
- History of eye or systemic diseases that may affect eye development
- Known allergy to fluorescein, benoxinate, proparacaine, or tropicamide
- Contact lens contraindications such as giant papillary keratoconjunctivitis
- Corneal disorders such as reduced corneal sensitivity or keratoconus
- Strabismus at distance or near while wearing glasses or contact lenses
- Poor personal hygiene that could affect contact lens wear compliance
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Alabama at Birmingham School of Optometry
Birmingham, Alabama, United States, 35233
Actively Recruiting
Research Team
S
Sindhu Gurrala, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here