Actively Recruiting

Phase Not Applicable
Age: 60Years - 85Years
All Genders
Healthy Volunteers
NCT05625425

Wayfinding Intervention and Long-Term Memory

Led by University of California, San Francisco · Updated on 2026-05-07

200

Participants Needed

1

Research Sites

160 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment. Cognitive training with an immersive video game promises to drive hippocampal-cortical plasticity and associated gains that can restore memory capability or provide therapeutic treatment for memory deficits.

CONDITIONS

Official Title

Wayfinding Intervention and Long-Term Memory

Who Can Participate

Age: 60Years - 85Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Fluent speakers of English
  • Completed 12 or more years of education
  • Normal or corrected-to-normal vision
  • Dexterity to comfortably operate the scanner-compatible response box
  • Freedom from physical and neurological conditions contra-indicated for fMRI
  • Must confirm physical stamina and comfort for semi-weekly brisk 30-minute walks on level ground
Not Eligible

You will not qualify if you...

  • Use of psychotropic medications
  • History of concussions or dizziness, vestibular or balance problems
  • Significant discomfort with virtual reality experiences

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

UCSF Mission Bay

San Francisco, California, United States, 94158

Actively Recruiting

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Research Team

M

Melissa Arioli

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

4

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