Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT07067866

Weaning Approaches for Vasopressin in Sepsis

Led by Hospital Nossa Senhora da Conceicao · Updated on 2026-01-02

82

Participants Needed

1

Research Sites

156 weeks

Total Duration

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AI-Summary

What this Trial Is About

In this study, we aim to evaluate the incidence of hypotension during vasopressin weaning by comparing two methods - titrated reduction versus abrupt withdrawal - through the conduct of a randomized clinical trial.

CONDITIONS

Official Title

Weaning Approaches for Vasopressin in Sepsis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18 years
  • Admitted to the Intensive Care Unit
  • Patients with vasopressor dependent sepsis
  • Receiving combined norepinephrine and vasopressin therapy
Not Eligible

You will not qualify if you...

  • Withdrawal or reduction of vasopressin due to a plan of treatment limitation or palliative care
  • Withdrawal or reduction of vasopressin associated with starting adrenaline or any other vasopressor

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Hospital Nossa Senhora da Conceição

Porto Alegre, Rio Grande do Sul, Brazil, 91350200

Actively Recruiting

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Research Team

W

Wagner Luis Nedel, Critical Care Physician, PhD

CONTACT

R

Rafael Barberena Moraes, Critical Care Physician, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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