Actively Recruiting

Phase Not Applicable
Age: 20Years +
All Genders
ID06630663

Effectiveness of a Wearable Device and AI-Supported Diet and Exercise Intervention in Obese Adults A Quasi-experimental Design Study

Led by National Taiwan University Hospital · Updated on 2026-03-25

120

Participants Needed

2

Research Sites

50 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying overweight and obese adults to evaluate the effectiveness of a 6-month personalized diet and exercise program aimed at promoting weight loss. This study focuses on different obesity levels and examines the role of galectin-1, a protein linked to inflammation and fat tissue, in relation to weight loss and metabolic changes. The research compares standard care with an intervention using wearable devices and artificial intelligence (AI) apps to support lifestyle changes. Participants are divided into two groups: one follows a standard diet and exercise program based on Mediterranean diet principles and physical activity guidelines, while the other group uses wearable devices and AI apps alongside the same program. The devices track steps, heart rate, and calories burned, and participants log their food intake using a smartphone app. The program includes outpatient visits at weeks 0, 12, and 24, with phone consultations at weeks 2, 4, and 8 to provide coaching and guidance. Weight loss medications are not allowed during the study. During the study, researchers measure participants' weight, height, blood pressure, waist circumference, body composition, and blood samples to assess glucose, cholesterol, triglycerides, insulin, and galectin-1 levels. Measurements are taken at the start and at week 24. Participants receive diet and exercise education, and case managers offer coaching through a health management platform. The main outcome measured is weight change after 24 weeks, along with secondary outcomes like waist size, blood pressure, and cholesterol levels.

CONDITIONS

Brief Title

A Wearable Device and AI-Supported Diet and Exercise Intervention

Who Can Participate

Age: 20Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • At least 20 years of age
  • Body mass index (BMI) of 24 kg/m2 or higher with one or more obesity-related conditions such as hypertension, diabetes, hyperlipidemia, sleep apnea syndrome, or nonalcoholic fatty liver disease
  • Ability to use a wearable device and a smartphone app
  • Ability to sign the informed consent form after receiving detailed study information
Not Eligible

You will not qualify if you...

  • Unable to complete self-administered questionnaires
  • Unable to complete body composition assessments, hand grip test, or blood sampling
  • Unable to attend scheduled clinic visits

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 6 months

Participants engage in a 6-month diet and exercise program. Some use a wearable device and AI-supported app to track their activity and diet, while others follow a standard diet and exercise plan. They receive face-to-face diet and exercise education and coaching from case managers.

3 outpatient clinic visits at week 0, week 12, and week 24, plus phone consultations at week 2, week 4, and week 8

Trial Site Locations

Total: 2 locations

1

National Taiwan University Hospital

Taipei, Taipei, Taiwan, 100

Actively Recruiting

2

National Taiwan University Hospital

Taipei, Taiwan, 100

Actively Recruiting

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Research Team

C

CW LU, A.P.

K

KC Huang, Professor

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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