Actively Recruiting
WearAble Technology for Collecting Health Data in People Who Are the Transfused (WATCH Transfused) - A UK Exploratory Study to Improve Quality of Life and the Efficacy of Transfusion Supportive Care in People With Blood Cancers Undergoing Treatment
Led by University of Oxford · Updated on 2026-04-06
80
Participants Needed
1
Research Sites
21 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cancer treatments like chemotherapy can harm healthy cells, leading to side effects such as anemia. Anemia may cause severe tiredness, shortness of breath, and brain fog, often requiring regular blood transfusions. Patients undergoing treatment frequently experience poor quality of life due to these side effects. Doctors currently use blood tests to determine when patients can start or continue treatment, but these tests do not always reflect how patients actually feel. This research aims to better understand patients' experiences during treatment and improve how blood transfusions are used to support their quality of life. Participants in this study will include 80 adults starting treatment for blood cancers such as Myelodysplastic Syndrome (MDS), Acute Myeloid Leukemia (AML), and myeloma. They will wear a device called the Axvitiy Ax3 accelerometer for two months to monitor their physical activity levels. Alongside this, participants will complete questionnaires about their symptoms and quality of life. Family members and carers may also be invited to interviews to share their perspectives on improving care and access to transfusions. During the study, researchers will compare physical activity data with patients' reported well-being and blood test results to find better ways to match transfusion support to individual needs. This personalized approach aims to help patients tolerate treatment more effectively. The study will involve ongoing assessments over two months, including activity monitoring and quality of life questionnaires, to gather comprehensive information about the impact of low blood counts and transfusions on patients' lives.
CONDITIONS
Brief Title
WearAble Technology for Collecting Health Data in People Who Are the Transfused (WATCH Transfused) - A UK Exploratory Study to Improve Quality of Life and the Efficacy of Transfusion Supportive Care in People With Blood Cancers Undergoing Treatment
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 years or older with WHO-defined Myelodysplastic Syndrome (MDS), mixed myeloproliferative/myelodysplastic neoplasm overlap syndromes, myeloma, or Acute Myeloid Leukemia (AML)
- Intention to start disease-modifying treatment
- Life expectancy of 6 months or more
- Ability to complete quality of life questionnaires
- Willingness and ability to provide informed consent for participation
- Willingness to receive blood products as part of normal NHS care
You will not qualify if you...
- Poor functional status (ECOG score 3 or higher)
- Known arrhythmias or significant heart conduction disorders
- Severe other health conditions (comorbidities)
- Known skin allergies or conditions that may affect safety or data quality
- Current hospitalization
- Participation in another interventional clinical study
- Presence of a pacemaker, implanted cardioverter defibrillator, or any cardiac implanted device
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 2 months
Participants wear the Axvitiy Ax3 accelerometer device to collect health data related to their activity.
Participants wear the device continuously during this period; specific visit schedule not defined
Trial Site Locations
Total: 1 location
1
Oxford University Hospitals NHS Trust
Oxford, OXFORDSHIRE, United Kingdom, OX39DU
Actively Recruiting
Research Team
M
Matthew H Poynton, MBBS
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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