Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
ID05663203

A Web-Based Dyadic Intervention to Manage Psychoneurological Symptoms for Patients With Colorectal Cancer and Their Caregivers

Led by Emory University · Updated on 2025-12-19

56

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

Sponsors

E

Emory University

Lead Sponsor

O

Oncology Nursing Society

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating a web-based dyadic intervention designed to help manage psychoneurological symptoms such as fatigue, depression, sleep problems, pain, and cognitive difficulties in patients with colorectal cancer who are receiving chemotherapy, along with support for their caregivers. These symptoms can severely affect both patient and caregiver quality of life and health outcomes. The study aims to develop and test this novel intervention to reduce symptom burden and improve well-being in cancer care. The intervention, called CRCweb, is developed through interviews and feedback from patient-caregiver pairs to tailor its content. The study includes a prototype usability test and then a pilot clinical trial where 20 patient-caregiver dyads participate in the web-based program over 8 weeks. Throughout this period, patients and caregivers engage with the intervention and complete interviews and surveys. Participants will be involved in surveys and interviews during the 8-week intervention to assess factors such as adherence, acceptability, and symptom changes. Researchers will measure fatigue, depression, sleep quality, pain, cognitive function, and overall quality of life. Health records will also be reviewed. This approach helps understand how feasible and helpful the CRCweb program may be for patients and caregivers managing colorectal cancer symptoms.

CONDITIONS

Brief Title

A Web-Based Dyadic Intervention for Colorectal Cancer

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years or older
  • Diagnosed with colorectal cancer
  • Life expectancy greater than 12 months
  • Currently receiving active chemotherapy
  • Self-reported at least two psychoneurological symptoms
  • Identified a primary caregiver who provides emotional and physical support
  • Have access to the Internet
  • Fluent in English
  • Caregivers aged 18 years or older
  • Caregivers are the primary support person
  • Caregivers have Internet access
  • Caregivers are fluent in English
Not Eligible

You will not qualify if you...

  • Patients with Karnofsky Performance Scale score less than 50
  • Caregivers with severe diseases such as cancer or heart disease

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit

Supportive Care Intervention

Duration - 8 weeks

Participants attend a web-based dyadic intervention (CRCWeb) alongside their caregivers to manage psychoneurological symptoms during chemotherapy.

Participants complete interviews and surveys throughout the 8 weeks

Trial Site Locations

Total: 1 location

1

Emory University/Winship Cancer Institute

Atlanta, Georgia, United States, 30322

Actively Recruiting

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Research Team

Y

Yufen Lin, PhD, RN

C

Canhua Xiao, PhD, RN

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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Published Research Related To This Trial

A Web-Based Dyadic Intervention to Manage Psychoneurological Symptoms for Patients With Colorectal Cancer and Their Caregivers: Protocol for a Mixed Methods Study.

Yufen Lin, Laura S Porter, Wonshik Chee...

https://pubmed.ncbi.nlm.nih.gov/37379055