Actively Recruiting
Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain
Led by Jafar Bakhshaie · Updated on 2026-03-13
50
Participants Needed
1
Research Sites
76 weeks
Total Duration
On this page
Sponsors
J
Jafar Bakhshaie
Lead Sponsor
N
National Center for Complementary and Integrative Health (NCCIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The investigator aims to conduct a feasibility randomized controlled trial (RCT) (N=50) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Toolkit for Resilient Life beyond Pain and Substance Use; Web-TIRELESS) versus web-based minimally enhanced usual care (Web-MEUC) among adult patients with a painful non-traumatic upper-extremity condition(s) (PNUC) and commorbid risky substance use. Deliverables: \[1\] Adapt and refine open pilot protocol, patient recruitment, and other study materials. \[2\] Assess the feasibility, acceptability, and credibility of Web-TIRELESS and Web-MEUC in preparation for future research.
CONDITIONS
Official Title
Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 years or older seeking outpatient care at the Hand and Arm Center
- Diagnosed with a non-traumatic painful upper-extremity condition
- Pain score greater than 4 on the Numerical Rating Scale
- Risky substance use with screening scores above thresholds for alcohol or other substances
- Own a smartphone, laptop, or computer with internet access
- Fluent in English
- Able and willing to participate in a live video focus group and asynchronous web-based intervention
You will not qualify if you...
- Participation in mind-body or specialized substance abuse treatment in the past 3 months
- Practicing mindfulness more than 45 minutes per week in the past 3 months
- Changed psychotropic medications in the past 3 months
- Serious untreated mental illness such as schizophrenia
- Suicidal thoughts with intent or plan
- Pregnancy
- Secondary gains that may bias motivation (e.g., pending disability claim)
- Moderate to severe cognitive impairment (score 4 or less on SPMSQ)
- History of surgery for the current upper-extremity condition within the past 6 months or plans for surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
Research Team
J
Jafar Bakhshaie, MD, PhD
CONTACT
K
Kozbi B Cliff, BS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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