Actively Recruiting

Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
NCT07421596

An 8-Week Study Evaluating Gut and Digestive Health After Use of a Dietary Supplement System

Led by SF Research Institute, Inc. · Updated on 2026-02-24

50

Participants Needed

1

Research Sites

10 weeks

Total Duration

On this page

Sponsors

S

SF Research Institute, Inc.

Lead Sponsor

L

Life Vantage

Collaborating Sponsor

AI-Summary

What this Trial Is About

This clinical research study is being conducted to evaluate gut and digestive health before and after the use of a dietary supplement system over an eight-week period. Gut and digestive health play an important role in overall health, including digestion, nutrient absorption, immune function, and metabolic balance. Changes in gut microbiota, inflammation, and intestinal barrier function may contribute to digestive symptoms such as bloating, discomfort, altered bowel habits, and reduced well-being. In this study, adult men and women with self-reported gastrointestinal symptoms will consume a dietary supplement system daily for eight weeks. The study will measure changes in gut and digestive health using objective stool-based laboratory biomarkers and validated symptom questionnaires. Stool samples will be collected at baseline and at the end of the study to evaluate markers related to microbial diversity, inflammation, immune activity, digestive function, and intestinal barrier integrity. Participants will also complete questionnaires throughout the study to assess gastrointestinal symptoms and subjective digestive health and well-being. The study will also monitor the safety and tolerability of the dietary supplement system during the study period.

CONDITIONS

Official Title

An 8-Week Study Evaluating Gut and Digestive Health After Use of a Dietary Supplement System

Who Can Participate

Age: 18Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female adults aged 18 to 80 years at screening
  • Willing and able to provide written informed consent
  • Able and willing to follow all study procedures including visits, questionnaires, and stool sample collection
  • Willing to collect stool samples at clinic or home as instructed
  • Willing to abstain from alcohol during the study
  • Proficient in English and able to complete electronic forms via smartphone
  • Able and willing to travel to the research site for scheduled visits
  • No known food allergies by self-report
  • Willing to maintain usual diet and lifestyle except as directed by the study
  • Self-reported gastrointestinal symptoms with specific GSRS score criteria
Not Eligible

You will not qualify if you...

  • Allergy or sensitivity to study product ingredients or herbal products
  • Medical conditions interfering with study participation or results, including malabsorption disorders, chronic gastrointestinal diseases, severe depression, or recent significant cardiovascular disease
  • Pregnant, breastfeeding, or planning pregnancy during the study
  • Partner pregnant or planning pregnancy without contraception use
  • History of cancer within 5 years
  • Active or occasional smoking
  • Current probiotic use unless discontinued 4 weeks prior
  • History of weight loss or bowel surgery
  • Active infection within past 3 months requiring treatment or hospitalization
  • Use of immunosuppressive medications within past year
  • History of seizure disorder or recent seizure medication use
  • History of HIV infection or organ transplant
  • Use of medications for chronic gastrointestinal conditions
  • Any condition deemed unsuitable by the Principal Investigator

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

San Francisco Research Institute

San Francisco, California, United States, 94132

Actively Recruiting

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Research Team

D

Dr. John Ademola

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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