Actively Recruiting

Phase Not Applicable
Age: 50Years - 90Years
All Genders
NCT06909916

Weight-Bearing CT and Conventional Periprosthetic Distal Knee Fractures

Led by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Updated on 2025-04-04

20

Participants Needed

1

Research Sites

45 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Total knee arthroplasty (TKA) is a surgical procedure commonly conducted for patients with end-stage knee osteoarthritis, often leading to improved pain relief and function. However, for patients that have suffered an associated periprosthetic fracture, a broken bone that occurs around the implant of a TKA, they may receive sub-optical care due to a lack of a trustworthy assessments for component fixation and fracture healing in the literature. The prevalence of TKA surgeries is increasing annually and is projected to rise further due to an ageing population and obesity issue. By extension to this primary surgery, more Canadians will require an invasive revision surgery that risks patient morbidity and mortality. Thus, it is imperative to set a standard for fixation and bone healing assessments to lessen revision burdens and improve patient outcomes. CT imaging can effectively visualize areas of incomplete bone ingrowth that may be hidden from overlapping anatomy on plain radiographs, which remains the go-to imaging modality for orthopaedic surgeons to assess periprosthetic fracture healing. The purpose of this prospective cross-sectional study is to examine the efficacy of weight-bearing CT as a diagnostic tool for 20 participants who experienced a distal femur periprosthetic fracture and underwent revision surgery using a fracture fixation plate and screws. Participants will be scanned under loaded and unloaded conditions. Radiographic outcomes will be evaluated, including bone segment displacement and its relation to participants' reports of pain.

CONDITIONS

Official Title

Weight-Bearing CT and Conventional Periprosthetic Distal Knee Fractures

Who Can Participate

Age: 50Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Underwent revision surgery for repair of a distal femur fracture around a primary total knee arthroplasty femoral component using a fracture fixation plate more than 1 year ago
  • Aged between 50 and 90 years
  • Body mass index up to 40 kg/m2
  • Able to provide informed consent
  • Able and willing to complete study assessments and follow instructions
Not Eligible

You will not qualify if you...

  • Does not understand English
  • Underwent revision surgery for reasons other than distal femur fracture repair
  • Received intramedullary nail or distal femur replacement
  • Unable to stand independently on one leg during the weight-bearing CT inducible displacement exam

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital - London Health Sciences Centre

London, Ontario, Canada, N6A 5A5

Actively Recruiting

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Research Team

B

Brent Lanting, MD

CONTACT

F

Farzan Mohammadreza, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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