Actively Recruiting
Weight-Bearing CT and Conventional Periprosthetic Distal Knee Fractures
Led by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Updated on 2025-04-04
20
Participants Needed
1
Research Sites
45 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Total knee arthroplasty (TKA) is a surgical procedure commonly conducted for patients with end-stage knee osteoarthritis, often leading to improved pain relief and function. However, for patients that have suffered an associated periprosthetic fracture, a broken bone that occurs around the implant of a TKA, they may receive sub-optical care due to a lack of a trustworthy assessments for component fixation and fracture healing in the literature. The prevalence of TKA surgeries is increasing annually and is projected to rise further due to an ageing population and obesity issue. By extension to this primary surgery, more Canadians will require an invasive revision surgery that risks patient morbidity and mortality. Thus, it is imperative to set a standard for fixation and bone healing assessments to lessen revision burdens and improve patient outcomes. CT imaging can effectively visualize areas of incomplete bone ingrowth that may be hidden from overlapping anatomy on plain radiographs, which remains the go-to imaging modality for orthopaedic surgeons to assess periprosthetic fracture healing. The purpose of this prospective cross-sectional study is to examine the efficacy of weight-bearing CT as a diagnostic tool for 20 participants who experienced a distal femur periprosthetic fracture and underwent revision surgery using a fracture fixation plate and screws. Participants will be scanned under loaded and unloaded conditions. Radiographic outcomes will be evaluated, including bone segment displacement and its relation to participants' reports of pain.
CONDITIONS
Official Title
Weight-Bearing CT and Conventional Periprosthetic Distal Knee Fractures
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Underwent revision surgery for repair of a distal femur fracture around a primary total knee arthroplasty femoral component using a fracture fixation plate more than 1 year ago
- Aged between 50 and 90 years
- Body mass index up to 40 kg/m2
- Able to provide informed consent
- Able and willing to complete study assessments and follow instructions
You will not qualify if you...
- Does not understand English
- Underwent revision surgery for reasons other than distal femur fracture repair
- Received intramedullary nail or distal femur replacement
- Unable to stand independently on one leg during the weight-bearing CT inducible displacement exam
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital - London Health Sciences Centre
London, Ontario, Canada, N6A 5A5
Actively Recruiting
Research Team
B
Brent Lanting, MD
CONTACT
F
Farzan Mohammadreza, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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