Actively Recruiting
Weight Loss and ExeRcise
Led by VA Office of Research and Development · Updated on 2025-04-27
99
Participants Needed
1
Research Sites
204 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Weight loss interventions for neurologically health individuals have established benefits for improving physical and psychosocial function. The investigators believe that Veterans who have had a stroke would realize similar benefits and that the effects would be enhanced with concurrent exercise training. The investigators will study the effects of a 15-week lifestyle management program to determine if it can effectively improve some of the physical and psychosocial problems common in Veterans who have had a stroke.
CONDITIONS
Official Title
Weight Loss and ExeRcise
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of stroke at least 6 months prior
- Body mass index (BMI) greater than 30 kg/m2
- Residual weakness in the lower extremity (Fugl-Meyer LE motor score less than 34)
- Ability to follow instructions, complete training and testing, and communicate exertion, pain, and distress
- Provide informed consent
- Clearance for participation by study cardiologist after exercise tolerance test
You will not qualify if you...
- Unable to walk at least 150 feet or experience intermittent claudication while walking
- Unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina, or dyspnea at rest or during activities of daily living
- Dementia
- Life expectancy less than 1 year
- History of deep vein thrombosis or pulmonary embolism within 6 months
- Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions
- Severe hypertension with resting systolic over 200 mmHg and diastolic over 110 mmHg
- Currently enrolled in a rehabilitation trial to improve motor or psychosocial recovery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ralph H. Johnson VA Medical Center, Charleston, SC
Charleston, South Carolina, United States, 29401-5703
Actively Recruiting
Research Team
S
Sarah A Jackson, BA MA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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