Actively Recruiting
Weight Reduction in CLBP
Led by Vrije Universiteit Brussel · Updated on 2025-05-25
84
Participants Needed
2
Research Sites
82 weeks
Total Duration
On this page
Sponsors
V
Vrije Universiteit Brussel
Lead Sponsor
R
Rotterdam University of Applied Sciences
Collaborating Sponsor
AI-Summary
What this Trial Is About
We will recruit overweight/ obese participants between the age of 18 and 65 with chronic nonspecific low back pain . The participants will be randomly assigned to one of two interventions (each lasting 10 weeks). All interventions will be delivered in a blended format and will be a combination of online education material and face-to-face sessions with a physical therapist. The first group (experimental intervention) will receive a behavioral weight reduction program combined with pain neuroscience education plus cognition-targeted exercise therapy. Participants in the second group (control intervention) will receive pain neuroscience education and cognition-targeted exercise therapy alone. Allocation to the groups will be at random. Participants and assessors will be blinded for group allocation. The primary outcomes is pain intensity. Secondary outcomes include other pain related outcomes, body composition, physical activity, sedentary behavior, dietary intake and function.
CONDITIONS
Official Title
Weight Reduction in CLBP
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Overweight (BMI �3E�3D 25 kg/m2) or obese (BMI �3E�3D 30 kg/m2) with chronic low back pain
- Non-specific low back pain for at least 3 months' duration
- Currently seeking care for low back pain
- Native Dutch speaker
- Access to internet and computer/tablet/smartphone
You will not qualify if you...
- Leg pain of 7 or higher (on a maximum of 10) on a numeric rating scale
- Evidence of specific spinal pathology such as hernia, spinal stenosis, spondylolisthesis, infection, spinal fracture, or malignancy
- Evidence of severe underlying comorbidity like diabetes, cardiovascular problems, or metabolic diseases
- BMI �3E�3D 40 kg/m2
- Being pregnant or having given birth in the past year
- Currently receiving dietary or exercise interventions
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Vrije Universiteit Brussel
Brussels, Belgium
Actively Recruiting
2
Rotterdam University of Applied Sciences
Rotterdam, Netherlands
Actively Recruiting
Research Team
A
Anneleen Malfliet, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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