Actively Recruiting

Age: 18Years - 40Years
All Genders
Healthy Volunteers
NCT07460687

Westlake Frequent-sampling Cohort

Led by Westlake University · Updated on 2026-03-10

20

Participants Needed

1

Research Sites

90 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This intensive longitudinal study investigates the day-to-day stability and natural fluctuations of the gut microbiome in healthy adults over a 15-day period. While the human gut microbiome is a complex ecosystem, its baseline stability in the absence of disease or medical intervention remains insufficiently characterized due to low sampling frequency in prior research. By recruiting healthy volunteers for continuous daily sampling, this study aims to map temporal community structures and evaluate the stability of core microbiota. Additionally, the research utilizes Continuous Glucose Monitoring (CGM) to explore the potential relationships between microbiome dynamics, daily dietary intake, and host glycemic stability.

CONDITIONS

Official Title

Westlake Frequent-sampling Cohort

Who Can Participate

Age: 18Years - 40Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants reside in Hangzhou
  • Age between 18 and 40 years
Not Eligible

You will not qualify if you...

  • Refusing or unable to give informed consent
  • Having chronic gastrointestinal diseases and taking daily relevant medications
  • Having metabolic diseases including diabetes, hypertension, and cardiovascular diseases
  • Having craniocerebral trauma, cancer, liver disease, kidney disease, other critical illness, or history of operation or medication
  • Having bulimia nervosa, post-traumatic stress disorder, chronic anxiety and depression, or other critical neuronal disorders or history of relevant medication
  • Being pregnant or lactating
  • History of alcohol or drug addiction, or smoking more than 15 cigarettes per day
  • Concurrently participating in other clinical trials

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Westlake University

Hangzhou, Zhejiang, China, 310024

Actively Recruiting

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Research Team

J

Ju-Sheng Zheng, PhD

CONTACT

J

Jiang-Hua Zhang, Bachelor

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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