Actively Recruiting

Phase 4
Age: 65Years - 110Years
All Genders
NCT06455813

What Laxative Should be Used After Hip Fracture Surgery?

Led by Odense University Hospital · Updated on 2025-07-31

375

Participants Needed

2

Research Sites

120 weeks

Total Duration

On this page

Sponsors

O

Odense University Hospital

Lead Sponsor

I

Independent Research Fund Denmark

Collaborating Sponsor

AI-Summary

What this Trial Is About

To conduct a randomized clinical trial to determine how best to prevent constipation after hip fracture surgery using laxatives.

CONDITIONS

Official Title

What Laxative Should be Used After Hip Fracture Surgery?

Who Can Participate

Age: 65Years - 110Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients who are undergoing acute hip fracture surgery at one of two orthopedic departments in the Southern Region of Denmark
  • Age 65 years or older
  • Able to speak and understand Danish
Not Eligible

You will not qualify if you...

  • Known chronic constipation based on Wexner constipation score
  • Use of laxatives at hospital admission
  • Participation in other similar clinical studies
  • Terminal illness
  • Being restrained
  • Being in isolation
  • Severe heart disease classified as New York Heart Association (NYHA) class III or IV
  • Severe chronic inflammatory bowel disease
  • Acute abdominal surgical conditions such as ileus, obstruction, or perforation
  • Difficulty swallowing tablets or oral liquids (dysphagia)
  • Toxic megacolon
  • Gastric emptying disorder
  • Severe electrolyte imbalances (potassium < 2.5 mmol/l or sodium < 125 mmol/l)
  • Allergies to any study medication ingredients
  • Pregnancy (pregnant women are excluded, but pregnancy tests are not done since women are expected to be postmenopausal)

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

Hospital Lillebælt, Kolding Hospital

Kolding, Denmark

Actively Recruiting

2

Odense University Hospital, Svendborg Hospital

Svendborg, Denmark

Actively Recruiting

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Research Team

A

Anton Pottegård

CONTACT

C

Carina Lundby

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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