Actively Recruiting

Phase Not Applicable
Age: 6Years - 59Years
All Genders
NCT06482944

Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes

Led by Vanderbilt University · Updated on 2026-03-06

30

Participants Needed

1

Research Sites

89 weeks

Total Duration

On this page

Sponsors

V

Vanderbilt University

Lead Sponsor

V

Vanderbilt University Medical Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study will address the following aims: Aim 1 (primary): Conduct a pilot RCT to evaluate the feasibility, acceptability, enrollment, and retention rates of adult-child pairs after a 12-week family-centered, non-calorie restricted whole foods diet. Feasibility: ≥80% participant retention and completion of study outcome measures. Acceptability: ≥75 adult diet satisfaction via survey report and/or perceived diet satisfaction via focus groups. Aim 2: Conduct a pilot RCT to evaluate the preliminary effectiveness of a non-calorie restricted whole foods diet on adult HbA1c at 12 weeks and adult/child diet quality during the 12-week intervention. Aim 2a: Evaluate intervention effects on HbA1c measures in adults with prediabetes. Hypothesis 2a: Adults randomized to the treatment group will have lower HbA1c measures at 12 weeks than those in the control group. Aim 2b: Evaluate intervention effects on the diet quality (via the 2020 HEI) of adults and children. Hypothesis 2b: Adults and children randomized to the treatment group will have a higher diet quality score during the 12-week intervention period compared to adults and children in the control group. Aim 3: Conduct family focus groups to understand how SDOH and individual/family needs and preferences may be perceived barriers or facilitators of diet adherence.

CONDITIONS

Official Title

Whole Food for Families: A Pilot RCT of a Dietary Guidelines-Based Intervention to Prevent Type 2 Diabetes

Who Can Participate

Age: 6Years - 59Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 25 to 59 years who are parents of a child or adolescent aged 6 to 18 years
  • Adults with a body mass index between 23 kg/m2 and less than 40 kg/m2
  • Adults with prediabetes confirmed by recent lab values and HbA1c test before enrollment
  • Adults without special dietary restrictions or food allergies prohibiting varied food consumption
  • Adults who speak English
  • Adults residing in Greater Nashville Tennessee and willing to attend Vanderbilt study visits
  • Adults without medical conditions limiting diet-related study participation (e.g., tube feeding, severe food allergy)
  • Adults able to participate in a 12-week home meal preparation and cooking program
  • Children aged 6 to 18 years at initial screening
  • Children with an index parent enrolled in the program
  • Children with body mass index at or above the 5th percentile for age and gender
  • Children without special dietary restrictions or food allergies prohibiting varied food consumption
  • Children with parental commitment to participate for 12 weeks
  • Children who speak English
  • Children residing in Greater Nashville Tennessee and living at home with the enrolled parent
  • Children without medical conditions limiting diet-related study participation
  • Children able to participate in a 12-week dietary program including provided dinners and snacks
Not Eligible

You will not qualify if you...

  • Adults with HbA1c test results outside the specified range during screening
  • Adults younger than 25 years or older than 59 years
  • Adults with body mass index less than 23 kg/m2 or 40 kg/m2 and above
  • Adults receiving care for complicated prediabetes requiring frequent monitoring
  • Adults currently in any weight loss program
  • Adults with a prior diagnosis of type 2 diabetes
  • Adults who do not speak English or have limited English proficiency
  • Adults with dietary restrictions, food allergies, or medical conditions prohibiting diet study participation
  • Adults with serious mental or neurological illness affecting consent or participation
  • Pregnant or nursing women
  • Adults taking medications for diabetes or weight loss
  • Adults living outside Greater Nashville Tennessee or unwilling to travel for visits
  • Adults not meeting other eligibility criteria as determined by pre-screen
  • Children younger than 6 years or older than 18 years
  • Children with body mass index below the 5th percentile for age and gender
  • Children without an eligible enrolled parent
  • Children without parental commitment to participate
  • Children who do not speak English or have limited English proficiency
  • Children with dietary restrictions, food allergies, or medical conditions prohibiting diet study participation
  • Children showing dissenting behaviors during baseline data collection
  • Children actively participating in any weight loss program
  • Children not meeting other eligibility criteria as determined by pre-screen

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Vanderbilt University School of Nursing

Nashville, Tennessee, United States, 37240

Actively Recruiting

Loading map...

Research Team

N

Nadia M. Sneed, PhD, MSN

CONTACT

K

Kylee Vecchi, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here