Actively Recruiting
Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDS
Led by Washington University School of Medicine · Updated on 2025-10-16
325
Participants Needed
1
Research Sites
328 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a single institution, prospective study of the whole genome sequencing assay, ChromoSeq. Using prospectively collected patient data, coupled with physician surveys, the investigators seek to determine the feasibility of implementing ChromoSeq in addition to standard genomic testing, for patients with the diagnoses of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
CONDITIONS
Official Title
Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in AML and MDS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient with a clinical suspicion for a new diagnosis of AML or MDS for whom diagnostic molecular testing is requested or planned
- Adult patients 18 years or older
- Ability to understand and willing to sign an IRB approved informed consent document
- Treating physician at Washington University School of Medicine directing therapy for hematologic malignancies
- Physician able and willing to complete questionnaires about ChromoSeq usability and perceptions during implementation
You will not qualify if you...
- Younger than 18 years
- Physician does not treat patients at Washington University School of Medicine
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Washington University School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
Research Team
M
Meagan Jacoby, M.D., Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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