Actively Recruiting
Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in MDS
Led by Washington University School of Medicine · Updated on 2025-12-11
60
Participants Needed
1
Research Sites
265 weeks
Total Duration
On this page
Sponsors
W
Washington University School of Medicine
Lead Sponsor
A
American Society of Hematology
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a single institution, prospective study of the whole genome sequencing assay, ChromoSeq. Using prospectively collected patient data, coupled with physician surveys, the investigators seek to determine the feasibility of implementing ChromoSeq in addition to standard genomic testing, for patients with the diagnosis of myelodysplastic syndrome (MDS).
CONDITIONS
Official Title
Whole Genome Sequencing (ChromoSeq) as an Adjunct to Conventional Genomic Profiling in MDS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of myelodysplastic syndrome (MDS) or clinical suspicion of new MDS diagnosis with planned routine diagnostic testing
- Seen in the outpatient setting
- Not previously treated with disease-modifying therapies such as lenalidomide or hypomethylating agents
- May have received transfusional support, erythropoietin-stimulating agents, growth factor support, or luspatercept
- At least 18 years old
- Able to understand and willing to sign an IRB-approved written informed consent form
You will not qualify if you...
- Younger than 18 years
- Does not treat patients at Washington University School of Medicine
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Washington University School of Medicine
St Louis, Missouri, United States, 63110
Actively Recruiting
Research Team
M
Meagan A Jacoby, M.D., Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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