Actively Recruiting

Age: 2Years - 20Years
All Genders
NCT02602769

Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

Led by Columbia University · Updated on 2025-10-21

12

Participants Needed

2

Research Sites

578 weeks

Total Duration

On this page

Sponsors

C

Columbia University

Lead Sponsor

N

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Rapid onset Obesity, Hypoventilation, Hypothalamic dysfunction and Autonomic Dysregulation (ROHHAD) is a syndrome named in 2007. The hallmark of the syndrome is the rapid onset obesity and dysregulation of central ventilation. There is little information about the metabolic changes that lead to the rapid onset obesity in these children. The investigators would like to study the metabolic phenotype of these children to understand the disturbances in energy balance that lead to the rapid onset obesity.

CONDITIONS

Official Title

Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome

Who Can Participate

Age: 2Years - 20Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children with ROHHAD syndrome
Not Eligible

You will not qualify if you...

  • Children with known genetic causes of obesity

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

Boston Children's Hospital

Boston, New York, United States, 02115

Completed

2

Columbia University Irving Medical Center

New York, New York, United States, 10032

Actively Recruiting

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Research Team

V

Vidhu Thaker, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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