Actively Recruiting
Wide Margin vs. Narrow Margin in Postneoadjuvant Lumpectomy
Led by Mansoura University · Updated on 2021-02-25
370
Participants Needed
1
Research Sites
365 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Breast cancer patients often receive systemic drugs as the initial curative treatment of their disease. The initial systemic therapy leads to a variable degree of tumor shrinkage. At present, there is no evidence-based consensus among breast surgeons on the optimal extent of resection after considerable tumor shrinkage and whether resection margin should be designed according to the tumor extent before treatment or the extent after treatment. This trial will help determine the optimal extent of resection in tumors that exhibits a significant change in volume after primary systemic therapy.
CONDITIONS
Official Title
Wide Margin vs. Narrow Margin in Postneoadjuvant Lumpectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Biopsy-proven diagnosis of invasive adenocarcinoma of the breast.
- Tumor stage T1 to T4b.
- Nodal stage N0 to N2.
- ASA (American Society of Anesthesiologists) class I or II.
You will not qualify if you...
- Patients choosing mastectomy.
- Patients advised by their doctor to have mastectomy.
- Patients choosing primary surgery instead of systemic therapy.
- Patients advised by their doctor to have primary surgery.
- Patients with metastatic breast cancer.
- Patients with multifocal tumors.
- Patients with lobular neoplasia.
- Current pregnancy or pregnancy less than 6 months before enrollment.
- Active second cancer.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mansoura University Oncology Center
Al Mansurah, DK, Egypt, 35516
Actively Recruiting
Research Team
O
Osama Hussein, MD,PhD,FEBS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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