Actively Recruiting

Age: 30Days +
All Genders
Healthy Volunteers
NCT06177639

Widefield Confocal Scanning Laser Ophthalmoscope Optimized for Pediatric and Neonatal Imaging

Led by Duke University · Updated on 2025-10-08

42

Participants Needed

1

Research Sites

43 weeks

Total Duration

On this page

Sponsors

D

Duke University

Lead Sponsor

N

National Eye Institute (NEI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to test the use of a novel Widefield Confocal Scanning Laser Ophthalmoscope (WiSLO) Optimized for Pediatric and Neonatal Imaging in pediatric and adult subjects who are undergoing clinical evaluation for eye disease or are healthy adult volunteers. The main questions to answer are: * Whether WiSLO will be more comfortable and satisfactory in experience for the patient and operator than commercial alternatives. * If the quality of WiSLO near infrared images will be comparable to color fundus camera imaging across population of different ages and fundus pigmentation. Participants will have the following research procedures: * Imaging of both eyes with a research noncontact WiSLO * Imaging of both eyes with a commercially available non-contact hand held fundus camera (Volk Pictor Plus) * Likert scales for adults * Pediatric Likert scales for children * CRIES scales for infants.

CONDITIONS

Official Title

Widefield Confocal Scanning Laser Ophthalmoscope Optimized for Pediatric and Neonatal Imaging

Who Can Participate

Age: 30Days +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 years or older, with or without eye diseases
  • Infants or children undergoing clinical eye evaluation, with or without eye diseases, excluding inpatient pre-term infants or neonates
  • Pediatric participants must be at least 30 days adjusted age
  • Adults and pediatric participants may have had prior pupil dilation for clinical care
  • Adult participants able and willing to consent to participate
  • Parent or legal guardian able and willing to consent for minors
  • Pediatric participants older than 12 years able and willing to assent to participation
Not Eligible

You will not qualify if you...

  • Participant or parent/legal guardian unwilling or unable to provide consent
  • Participant has a health or eye condition preventing eye examination or retinal imaging, such as inflammation, infection of ocular surface or eyelids, corneal opacity, or cataract

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Duke University Eye Center

Durham, North Carolina, United States, 27710

Actively Recruiting

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Research Team

C

Cynthia A Toth, MD

CONTACT

M

Michelle N McCall, MCAPM, BA

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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