Actively Recruiting
WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)
Led by University of Florida · Updated on 2026-02-10
120
Participants Needed
1
Research Sites
107 weeks
Total Duration
On this page
Sponsors
U
University of Florida
Lead Sponsor
N
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking. This study will also examine whether non-invasive transcutaneous vagal nerve stimulation (tVNS) intervention initiated 30 days post-surgery improves brain function and thinking. The study does NOT cover any costs associated with bariatric surgery.
CONDITIONS
Official Title
WISE-2B Brain Study (Weight Loss Intervention Surgical Effects on Brain Function)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between age: 20-75 yrs, English speaking, Physically mobile
- Body Mass Index (BMI) >35 kg before surgery
- Compatible of MRI Scanning
- Willing to give a small blood sample
- Capable of providing informed consent
You will not qualify if you...
- Prior or current neurological disorder
- Major psychiatric disturbance
- Unstable medical conditions (cancer)
- MRI contraindications (claustrophobia, metal implants, waist/torso circumference)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Florida - College of Public Health and Health Professions
Gainesville, Florida, United States, 32611
Actively Recruiting
Research Team
K
Keyanni J Johnson
CONTACT
R
Ronald Cohen, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
FACTORIAL
Primary Purpose
OTHER
Number of Arms
4
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