Actively Recruiting
WMT for Autism Spectrum Disorder (ASD)
Led by The Second Hospital of Nanjing Medical University · Updated on 2025-09-05
80
Participants Needed
2
Research Sites
188 weeks
Total Duration
On this page
Sponsors
T
The Second Hospital of Nanjing Medical University
Lead Sponsor
N
Nanjing Medical University
Collaborating Sponsor
AI-Summary
What this Trial Is About
Autism Spectrum Disorder (ASD) is a group of serious neurodevelopmental disorders. A significant comorbidity exists between ADHD and ASD: 30%-50% of individuals with ASD exhibit ADHD symptoms, and two-thirds with ADHD show ASD traits. Intestinal microbial disturbance is common in children with ASD. A great deal of evidence shows that intestinal microbes can influence the brain to play its role through "gut-brain-microbiota axis". We intend to explore the role of Washed Microbiota Transplantation in improving symptoms of children in ASD with or without ADHD; To study the potential etiological mechanism of WMT for the neurodevelopmental disorders.
CONDITIONS
Official Title
WMT for Autism Spectrum Disorder (ASD)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children and adolescents diagnosed with ADHD or both ADHD and Autism Spectrum Disorder according to DSM-5
- Age between 3 and 17 years
- Stable treatments for at least 1 month before starting Washed Microbiota Transplantation
You will not qualify if you...
- Guardian unable to understand questionnaires or provide informed consent
- Diagnosis of single-gene disorder, major brain malformations, or gastrointestinal diseases such as ulcerative colitis, Crohn's disease, or eosinophilic esophagitis
- Severe comorbid conditions including cardiopulmonary failure, severe liver or kidney disease, severe infection, or tumors
- Presence of other life-threatening disorders requiring emergency treatment
- Inability to tolerate colonoscopy or anesthesia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Department of Microbiota Medicine & Medical Centre for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China
Actively Recruiting
2
SIR RUN RUN hospital of Nanjing Medical University
Nanjing, Jiangsu, China
Actively Recruiting
Research Team
F
Faming Zhang, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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