Actively Recruiting
Women SHINE: Addressing Syndemics and HIV Among Women Through Tech-Based Peer Engagement
Led by University of California, San Diego · Updated on 2025-10-20
360
Participants Needed
1
Research Sites
198 weeks
Total Duration
On this page
Sponsors
U
University of California, San Diego
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
A two-arm RCT will be conducted to test the efficacy of Women SHINE, a web-based trauma-informed peer navigation-social support intervention (Figure 2). A total of 360 women living with HIV/AIDS (WLHA) with a history of adulthood interpersonal violence who have been prescribed ART but are non-adherent (\< 90% ART adherent in the last 4 weeks) will be enrolled in the study. WLHA will be randomized (1:1) into one of the following conditions: 1) Women SHINE intervention arm (n=180) or 2) Control arm (n=180). The Women SHINE intervention arm will receive a four-month intervention including peer navigator (PN) one-on-one sessions, phone/text-based check-ins, 7 psychoeducation weekly support group sessions (120 mins.) co-facilitated by a licensed therapist and PN, and access to a static website with resources for HIV care, interpersonal violence, trauma, mental health, and substance use. The control arm will receive one group session (60 mins.) on self-care and well-being and access to the aforementioned website with resources. Women will complete a video-based survey and mailed hair sample self-collection at baseline, 4-, 8-, and 12-months post-randomization, to evaluate improvements in ART adherence (Aim 1), emotion regulation, and PTSD symptoms (Aim 2). Investigators will examine the mediating effect of individual (retention in HIV care, coping self-efficacy, social support, ancillary support services use) and socio-structural (stigma, medical mistrust) mechanisms of change on the efficacy of Women SHINE (Aim 3).
CONDITIONS
Official Title
Women SHINE: Addressing Syndemics and HIV Among Women Through Tech-Based Peer Engagement
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Cisgender female
- Diagnosed with HIV by a physician, healthcare provider, or community health worker
- Aged 18 years or older
- Able to speak and read English or Spanish
- Experienced interpersonal violence during adulthood
- Currently prescribed antiretroviral therapy (ART)
- Self-reported less than 90% adherence to ART in the past month
- Not currently participating in another adherence intervention
- Access to an internet browser
You will not qualify if you...
- Unwilling to participate in the intervention
- Transgender female
- No diagnosis of HIV by a physician, healthcare provider, or community health worker
- Under 18 years of age
- Unable to speak or read English or Spanish
- Not currently prescribed ART
- Self-reported 90% or greater adherence to ART in the past month
- Currently participating in another adherence intervention
- No access to an internet browser
- Cognitive impairment that limits ability to give informed consent
- Experienced only childhood interpersonal violence
- Unable to safely participate in the study based on secondary screening
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
The Regents of the Univ. of Calif., U.C. San Diego
La Jolla, California, United States, 92093
Actively Recruiting
Research Team
C
Cassandra Cyr, MPH
CONTACT
J
Jamila K Stockman, PhD, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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