Evaluation of Triclosan-Coated Versus Standard Absorbable Sutures for Healing After Lower Impacted Wisdom Tooth Removal in Adults 18 to 35 Years

What this Trial Is About

Researchers are evaluating whether triclosan-coated absorbable stitches help improve soft tissue healing and reduce bacterial buildup compared to standard stitches after lower impacted wisdom tooth removal in adults aged 18 to 35 years. This randomized, double-blind, crossover clinical trial aims to compare healing outcomes and bacterial adherence on sutures during the first week after surgery. The crossover design allows each participant to serve as their own control by receiving both types of stitches in separate surgeries. Participants will undergo two surgeries to remove symmetrical impacted lower wisdom teeth about four weeks apart. In one surgery, they will receive triclosan-coated polyglactin 910 sutures, and in the other, non-coated polyglactin 910 sutures. The order of suture type is randomly assigned. Follow-up visits occur on postoperative days 3, 5, and 7 for each surgery to assess healing, pain, swelling, and to collect suture samples for bacterial testing. During the study, participants will have their wounds examined clinically and bacterial load measured using laboratory tests on collected suture segments. Pain and swelling are rated using simple scales. The trial monitors healing progress at specific days after each surgery to compare the two suture types within the same individual. Participants are expected to attend all follow-up visits, and the total study duration spans the time needed to complete both surgeries and follow-ups.

Wound Healing and Bacterial Adherence With Triclosan-Coated Sutures After Mandibular Impacted Third Molar Surgery