Actively Recruiting
Wound Healing Following Tooth Extraction and Ridge Preservation Using OsteoGen®
Led by The University of Texas Health Science Center at San Antonio · Updated on 2026-01-06
44
Participants Needed
1
Research Sites
110 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
After the removal of a tooth, a bone graft is often placed in the socket to try to keep the volume of bone that was there when the tooth was present so that the bone does not "shrink". The bone graft is sometimes kept in place with a small piece of material over the top of the tooth socket and with stitches. This procedure is called "Ridge Preservation". Many different materials are used for ridge preservation including bone allografts (bone grafts derived from a human tissue donor), bone xenografts (bone grafts derived from species other than humans, such as cows and pigs), and synthetic materials that are similar in structure to bone (such as calcium apatite). The bone allograft and the calcium apatite product used in this study are Food and Drug Administration (FDA) approved. This study will compare the two methods used to see how much new bone formation there is inside the tooth socket at about 16 weeks of healing after ridge preservation with a calcium apatite/collagen sponge versus an allograft.
CONDITIONS
Official Title
Wound Healing Following Tooth Extraction and Ridge Preservation Using OsteoGen®
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female patient aged 18 to 89
- One tooth, excluding molars, that requires a single tooth extraction
- A dental implant is planned to replace the missing tooth
- The site has enough space for a dental implant restoration
- The site has at least 10 mm of alveolar bone height without affecting the sinus or nerve canal
- The tooth socket has a bone plate defect extending no more than 50% of the socket depth
- Female patients who have had a hysterectomy, tubal ligation, menopause, or are nonpregnant women of child-bearing potential
- Nonsmokers or former smokers; current smokers included if smoking 10 or fewer cigarettes per day
You will not qualify if you...
- Allergy to bovine collagen products, Bacitracin, Gentamicin, or Polymyxin
- Unwillingness or inability to follow the study schedule
- Mentally incompetent individuals, prisoners, or pregnant women
- Pregnant women or women planning pregnancy during the study
- Smokers who smoke more than 10 cigarettes per day
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Texas Health Science Center at San Antonio School of Dentistry
San Antonio, Texas, United States, 78229
Actively Recruiting
Research Team
B
Brian Mealey, DDS, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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